Increased myocardial echo density in left ventricular pressure and volume overload in human aortic valvular disease: an ultrasonic tissue characterization study

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
V Di BelloC Giusti

Abstract

Quantitatively assessed ultrasonic backscatter is an index of ultrasonic tissue characterization directly related to morphometrically evaluated collagen in human beings. Our objective was to assess myocardial reflectivity pattern of patients with severe left ventricular hypertrophy caused by either aortic stenosis (AS) or aortic regurgitation (AR). Ten patients with AS, 10 patients with AR, and 10 closely age- and gender-matched healthy controls were studied by two-dimensional Doppler echocardiography. By using an echocardiographic prototype, we performed a radiofrequency analysis to obtain quantitative operator-independent measurements of the integrated backscatter signal of the ventricular septum and the posterior wall (integrated backscatter index: IBI, expressed in percentage). All patients with stenosis or aortic insufficiency showed a normal regional and global resting systolic function (fractional shortening: AS = 36.0 +/- 6.6 versus AR = 40.3 +/- 6.2 versus control = 40.2 +/- 8.7; p = not significant [NS]) Left ventricular mass index (Devereux's formula) was markedly increased in patients with stenosis or aortic insufficiency (AS = 199.3 +/- 18 versus AR = 208.8 +/- 60 versus control = 97.3 +/- 11 g/m2; p < 0.0001). Myo...Continue Reading

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Citations

Jul 22, 1999·European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology·M ZuberP Erne
Mar 6, 2003·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Giuseppe PacileoRaffaele Calabrò
Dec 20, 2007·Journal of Clinical Ultrasound : JCU·Andrzej MinczykowskiHenryk Wysocki
Aug 16, 2013·Biomedical Chromatography : BMC·Małgorzata Dołowy, Alina Pyka
Nov 14, 2006·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Marcin FijalkowskiAndrzej Rynkiewicz

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