Increased oxidative stress and oxidative damage associated with chronic bacterial prostatitis

Asian Journal of Andrology
Jun-Fu ZhouShu-Mei Zhang

Abstract

To investigate whether chronic bacterial prostatitis might increase oxidative stress and oxidative damage in chronic bacterial prostatitis patients (CBPP), and to explore its possible mechanism. Enrolled in a case-control study were 70 randomly sampled CBPP and 70 randomly sampled healthy adult volunteers (HAV), on whom plasma nitric oxide (NO), vitamin C (VC), vitamin E (VE) and beta-carotene (beta-CAR) level, erythrocyte malondialdehyde (MDA) level, as well as erythrocyte superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) activities were determined by spectrophotometry. Compared with the HAV group, values of plasma NO and erythrocyte MDA in the CBPP group were significantly increased (P < 0.001); those of plasma VC, VE and beta-CAR as well as erythrocyte SOD, CAT and GPX activities in the CBPP group were significantly decreased (P < 0.001). Findings from partial correlation for the 70 CBPP showed that with prolonged course of disease, values of NO and MDA were gradually increased (P < 0.001), and those of VC, VE, beta-CAR, SOD, CAT and GPX were gradually decreased (P < 0.05-0.001). The findings from stepwise regression for the 70 CBPP suggested that the model was Y = -13.2077 + 0.1894MDA + 0.0415NO - ...Continue Reading

References

May 9, 2001·Biochimica Et Biophysica Acta·G HsiaoM H Yen
Jan 5, 2002·Physiological Reviews·Wulf Dröge
Jan 25, 2002·Annals of the New York Academy of Sciences·W G NelsonT W Kensler
Jun 25, 2002·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Avedis Meneshian, Gregory B Bulkley
Oct 11, 2003·Andrologia·J M Potts, F F Pasqualotto
Feb 26, 2004·Cerebrovascular Diseases·Konstantinos SpengosDemetris Vassilopoulos
Feb 3, 2005·Asian Journal of Andrology·Yu-Ping DaiKe-Li Zheng
Nov 11, 2005·Asian Journal of Andrology·Ja-Hyeon KuSoo-Woong Kim

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Citations

Nov 3, 2010·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Sang Hoon KimYong-Hyun Cho
Oct 9, 2007·International Journal of Antimicrobial Agents·Chang Hee HanYong-Hyun Cho
Dec 7, 2007·The Urologic Clinics of North America·David StockD Robert Siemens
Aug 12, 2010·FEMS Immunology and Medical Microbiology·Sławomir LetkiewiczAndrzej Górski
Mar 23, 2017·Antioxidants & Redox Signaling·Amy J BurkeSharon A Glynn
Dec 5, 2009·Critical Reviews in Clinical Laboratory Sciences·Daniela GiustariniRanieri Rossi
Jul 22, 2020·Andrologia·Ralf HenkelDavid Fisher
Oct 27, 2017·Clinical Science·Naomi LomeliKelvin J A Davies
May 20, 2020·Frontiers in Pharmacology·Situ XiongBin Fu
Jan 23, 2020·Antioxidants·Nuria Rubio-RiquelmeRosa María Martínez-Espinosa

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