Abstract
Previous studies showed that both inflammation and platelets have a role in development of slow coronary flow (SCF). Platelet to lymphocyte ratio (PLR) as an emerging inflammatory indicator was significantly associated with adverse cardiovascular events. Therefore, we aimed to assess the relationship between PLR and SCF. Patients who had angiographically normal coronary arteries were enrolled in this retrospective study (n = 221 as SCF group and n = 293 as control group). Patients who had thrombolysis in myocardial infarction frame counts (TFC) above the normal cutoffs were considered to have SCF. Both PLR and C-reactive protein (CRP) were significantly higher in the SCF group. In correlation analysis, PLR has a significantly positive correlation with the left anterior descending artery TFC (P = .001), circumflex artery TFC (P < .001), right coronary artery TFC (P < .001), and serum CRP level (P < .001). In multiple logistic regression analysis, PLR was independently associated with presence of SCF (odds ratio: 1.014, P < .001). In conclusion, higher PLR levels were significantly and independently related to the presence of SCF. Besides, PLR was positively correlated with serum CRP level as a conventional marker for systemic in...Continue Reading
References
Nov 1, 1986·Circulation·M MosseriY Hasin
Jul 1, 1972·American Heart Journal·A A TambeE Mascarenhas
Mar 1, 1996·Circulation·C M GibsonE Braunwald
Aug 22, 2001·Angiology·P K GoelA Kapoor
Mar 26, 2003·Coronary Artery Disease·Alpay Turan SezginSengul Cehreli
Apr 9, 2005·Clinical Cardiology·Mustafa GökçeMehmet Küçükosmanoğlu
Jul 9, 2005·International Journal of Cardiology·Hasan TurhanErtan Yetkin
Aug 2, 2005·International Journal of Cardiology·Basri AmasyaliErsoy Isik
Jul 27, 2007·Angiology·Irfan BarutcuSengul Cehreli
Aug 21, 2007·Clinica Chimica Acta; International Journal of Clinical Chemistry·Jian-Jun LiJie Li
Jun 6, 2009·Journal of Thrombosis and Thrombolysis·Turgay CelikErsoy Isik
Apr 14, 2010·Medical Hypotheses·Xiao WangShao-Ping Nie
Apr 3, 2012·Journal of Thrombosis and Thrombolysis·Basem AzabJoseph T McGinn
Apr 25, 2013·Korean Circulation Journal·Taner Sen
Jun 22, 2013·Clinical and Experimental Hypertension : CHE·Murat SunbulAltug Cincin
Jul 31, 2013·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Mehmet DoganEkrem Yeter
Oct 9, 2013·Angiology·Ahmet EkmekciMehmet Eren
Feb 11, 2014·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Eman M SherifSamar F Mohamed
Feb 21, 2014·Atherosclerosis·Natale Daniele BrunettiMatteo Di Biase
May 8, 2014·Coronary Artery Disease·Gokhan AksanMahmut Sahin
Jun 10, 2014·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Murat UgurMehmet Eren
Jul 9, 2014·Journal of Thrombosis and Thrombolysis·Handan Inonu KoseogluOsman Demir
Oct 31, 2014·Coronary Artery Disease·Ying XuMin Pan
Citations
Jul 22, 2015·Platelets·Mehmet Kadri AkbogaDursun Aras
Oct 21, 2016·Indian Journal of Pharmacology·Edem EfeAkdeniz Bahri
Jul 7, 2016·Angiology·Xi-Peng SunQi Hua
Jul 15, 2016·Perfusion·Samad GhaffariLeili Pourafkari
Apr 30, 2019·Angiology·Alparslan Kurtul, Ender Ornek
Feb 14, 2019·Platelets·Kanupriya MathurRehan Qayyum
Oct 17, 2019·Revista da Associação Médica Brasileira·Emrah Erdal, Mehmet İnanir
Sep 21, 2019·BMJ Open·Ailifeire MaimaitiYi-Tong Ma
Jul 29, 2020·Angiology·Zhiqiang QiuXiaoshu Cheng
May 29, 2020·BMC Cardiovascular Disorders·Yao-Dong DingHai-Long Ge
Dec 18, 2020·Microvascular Research·Armin NowroozpoorBasmah Safdar
Mar 30, 2021·Angiology·George Chalikias, Dimitrios Tziakas
Mar 30, 2021·Frontiers in Cardiovascular Medicine·Shasha YuYingxian Sun
Dec 17, 2019·JACC. CardioOncology·Noriaki TabataJan-Malte Sinning
Oct 12, 2021·Angiology·Mehmet Kadri Akboga, Ibrahim Halil Inanc