Increased prevalence of essential hypertension in areas previously exposed to fallout due to nuclear weapons testing at the Semipalatinsk Test Site, Kazakhstan

Environmental Research
Akbayan MarkabayevaTatyana Belikhina

Abstract

This study examines the association between environmental radiation exposure and essential hypertension in a series of investigated geographical districts adjacent to the Semipalatinsk nuclear test site in Kazakhstan. The sample consists of 2000 volunteers participants in screening examinations in three administrative districts close to the nuclear test site, which was carried out as part of the Government Programs on Environmental Health Hazard. The cross-sectional study compares prevalence ratios in a population sample with long-term exposure in the low and intermediate dose range. Age-adjusted odds ratios for hypertension were found significantly increased with higher exposure groups. After accounting for main cardiovascular risk factors into the model and stratifying by gender, the prevalence odds ratios for radiation remained significantly increased, with a significant dose-response effect observed for some but not all subgroups. The results support existing evidence of cardiovascular health effects of radiation exposure and of persisting environmental health issues that require attention in both epidemiological surveys and healthcare provision.

Citations

Feb 18, 2020·Archives of Toxicology·Geir BjørklundSalvatore Chirumbolo
Jul 9, 2020·Environmental Science and Pollution Research International·Yuliya SemenovaGeir Bjørklund
May 8, 2021·Vavilovskiĭ Zhurnal Genetiki I Selekt︠s︡ii·A B BigalievM N Burkhanova

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