PMID: 8959949Dec 1, 1996Paper

Increased proportion of aggressive-growth basal cell carcinoma in the Veterans Affairs population of Palo Alto, California

Journal of the American Academy of Dermatology
D A WroneP A Khavari

Abstract

We have noted a high frequency of aggressive-growth basal cell carcinomas (BCCS) in our patient population. Subtypes observed with increased frequency include morpheaform, infiltrative, and micronodular. Our purpose was to examine the frequency of histologic subtypes of all BCCs seen in the dermatology clinics in the Veterans Affairs Palo Alto Health Care System in an 18-month period. We reviewed 432 consecutive primary BCC biopsy specimens taken from 252 patients. Aggressive-growth BCC was observed in 20.7% of biopsy specimens, including 13.4% morpheaform, 5.7% infiltrative, and 1.6% micronodular subtypes. The mean age of the patient population was 70 years, with a standard deviation of 9.1 years. Our observed percentage of aggressive-growth BCC is substantially higher than in most other large studies. A high frequency of aggressive-growth BCC coupled with the increasing incidence of nonmelanoma skin cancer may have significant implications for future health care resource allocation.

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Citations

Dec 14, 1999·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·D A GastonD P Clark
Apr 19, 2000·The American Journal of Dermatopathology·C I Brown, A E Perry
Sep 2, 1998·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·M S JonesE M Billingsley
Nov 24, 1998·Journal of Cutaneous Pathology·S M SwetterB M Egbert
May 10, 2006·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Philip R CohenBruce R Nelson
Oct 14, 2014·The British Journal of Dermatology·E TanS G J Ng
Jul 20, 1999·Journal of the American Academy of Dermatology·E B RussellB R Smoller
Jan 12, 2007·International Journal of Dermatology·Gursoy Dogan
Feb 6, 2007·Journal of Cutaneous Medicine and Surgery·William LearChristian A Murray
Nov 1, 2005·Machine Learning·W John WilburWon Kim
Jul 5, 2007·The Journal of Behavioral Health Services & Research·Jodie A TraftonElizabeth Oliva
Jul 16, 2021·Journal of Cutaneous Medicine and Surgery·Lina BelmeskElena Netchiporouk

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