PMID: 11334842May 4, 2001Paper

Increased QT dispersion in patients with Prinzmetal's variant angina and cardiac arrest

Cardiovascular Research
N ParchureJ C Kaski

Abstract

We sought to compare QT dispersion in patients presenting with Prinzmetal's variant angina complicated by cardiac arrest or syncope and patients with uncomplicated variant angina. Despite the usually benign course of treated Prinzmetal's variant angina, a proportion of vasospastic angina patients develop ventricular arrhythmias and sudden death in association with coronary spasm. Increased QT dispersion has been suggested to increase susceptibility to ventricular arrhythmias in patients with coronary artery spasm. We studied 25 consecutive patients (mean age 58 years; 14 men) with classical Prinzmetal's variant angina and documented coronary artery spasm. None of the patients had coronary artery stenoses < or =40%. Five patients had suffered a documented cardiac arrest, two had recurrent syncope and 18 had no arrhythmic events or syncopal episodes. In all patients QT dispersion (QT maximum-QT minimum in every ECG lead) was measured on the baseline 12-lead electrocardiogram at study entry using a digitising board. Mean (+/-S.D.) QT dispersion of study patients was 62.3+/-19.5 ms. QT dispersion in patients with cardiac arrest and syncope (79.4+/-17.3 ms) was significantly higher compared to patients with no such events (56.3+/-16...Continue Reading

Citations

Nov 2, 2012·Journal of the American Veterinary Medical Association·Samuel J Gabriel Filho, César A Ribeiro
Sep 30, 2014·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Antonio Bayés de LunaGünter Breithardt
Aug 13, 2014·Therapeutic Advances in Cardiovascular Disease·Aysel AkhundovaOsman Yesildag
Jul 9, 2016·Journal of the American College of Cardiology·Jung-Min AhnSeung-Jung Park
Mar 10, 2018·Current Cardiology Reports·Amartya KunduNaomi F Botkin
Aug 12, 2017·The Korean Journal of Internal Medicine·Ki Hong LeeJong Chun Park
Apr 19, 2018·Pacing and Clinical Electrophysiology : PACE·Tetsuji ShinoharaNaohiko Takahashi
Dec 20, 2017·Journal of Arrhythmia·Mitsuhiro Nishizaki

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