PMID: 8612024Feb 1, 1996Paper

Increased rate of lupus flare during pregnancy and the puerperium: a prospective study of 78 pregnancies

British Journal of Rheumatology
G Ruiz-IrastorzaN M Buchanan

Abstract

The objective was to determine whether the frequency of flare in systemic lupus erythematosus (SLE), patients is increased during pregnancy and the puerperium. Seventy-eight pregnancies in 68 SLE patients attending the lupus pregnancy clinic, at St. Thomas' Hospital, during the last 5 yr were included. The pregnancy period and 8 weeks post-delivery were considered. This group was compared with a control group of 50 consecutive, non-pregnant, age-matched SLE patients attending our weekly lupus clinic. Additionally, 43 of the pregnant patients carried on attending the lupus clinic for the year after puerperium, and their course was compared with themselves during pregnancy. SLE activity was assessed using the Lupus Activity Index (LAI) score. An increase > or = 0.26 in the score was considered as a flare of the disease. Pregnancy and control groups were homogeneous for age, race, disease duration and distribution of autoantibodies. Sixty-five per cent of the patients flared during pregnancy and/or the puerperium and 42% flared in the control group (P = 0.015). The rates of flare per patients/month were 0.082 +/- 0.004 for the pregnancy group and 0.039 +/- 0.003 for the control group (P < 0.001). The 43 patients whose course was c...Continue Reading

Citations

May 4, 2006·Zeitschrift für Rheumatologie·G Ruiz-Irastorza, M A Khamashta
Dec 4, 2012·Zeitschrift für Rheumatologie·M Haubitz
Aug 4, 2010·Archives of Gynecology and Obstetrics·Neelam AggarwalAman Sharma
Sep 26, 2006·Journal of Neurology·Isabel Ringel, Uwe K Zettl
May 23, 2007·Clinical Rheumatology·Javier A CavallascaGustavo G Nasswetter
Nov 7, 2008·Clinical Rheumatology·Stephanie O Keeling, Anna E Oswald
Jan 27, 2012·Clinical Rheumatology·Miguel A SaavedraLuis J Jara
Mar 12, 2011·Clinical Reviews in Allergy & Immunology·Haruko IdeguchiYoshiaki Ishigatsubo
Apr 14, 2005·Best Practice & Research. Clinical Endocrinology & Metabolism·Lorin Lakasing, Catherine Williamson
Nov 19, 2013·Best Practice & Research. Clinical Rheumatology·Aisha Lateef, Michelle Petri
Jul 3, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·F CarmonaJ Balasch
Jul 10, 2003·Autoimmunity Reviews·Ricard CerveraJuan Balasch
Dec 13, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Norella C T Kong
Nov 28, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Clara J DayCaroline O S Savage
Sep 15, 2000·Rheumatology·P E GeorgiouA A Drosos
Apr 1, 1999·The Australian & New Zealand Journal of Obstetrics & Gynaecology·N AggarwalP Bambery
Oct 12, 1999·American Journal of Reproductive Immunology : AJRI·N KobayashiS Fujimoto
Apr 9, 2005·Annals of the Rheumatic Diseases·M JohanssonS Rantapää-Dahlqvist
Jul 1, 1996·Annals of the Rheumatic Diseases·N M BuchananG R Hughes
May 15, 2001·Annals of the Rheumatic Diseases·D L HuongJ C Piette
Nov 3, 2007·BMJ : British Medical Journal·Lucy H MackillopCatherine Nelson-Piercy
Feb 27, 2001·Postgraduate Medical Journal·C C Mok, R W Wong
Apr 2, 2010·Pediatric Rheumatology Online Journal·Melissa S TesherKaren B Onel
Mar 16, 2012·Arthritis Research & Therapy·Andrea DoriaMichelle Petri
Feb 24, 2001·Hypertension Research : Official Journal of the Japanese Society of Hypertension·A ItoG Kimura
Aug 7, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Andrew SmythVesna D Garovic
Jan 11, 2007·Clinical Medicine & Research·Josephine Patricia Dhar, Robert J Sokol
Jun 29, 2013·Archives of Gynecology and Obstetrics·Riza MadazliHandan Yilmaz
Oct 30, 2013·Nature Reviews. Rheumatology·Wen Xiong, Robert G Lahita
Apr 11, 2001·Lancet·G Ruiz-IrastorzaG R Hughes
Jun 19, 2013·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Medha Barbhaiya, Bonnie L Bermas
Sep 12, 2003·Current Rheumatology Reports·Doruk Erkan, Lisa Sammaritano
Jun 1, 2005·Rheumatic Diseases Clinics of North America·Carl A LaskinKaren A Spitzer
Mar 21, 1998·Cardiology Clinics·D Perloff
Feb 4, 2010·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·R MadazliO Guralp
Sep 9, 2005·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·L SoubassiN Zerefos
Nov 25, 2011·Expert Review of Clinical Pharmacology·M Yousuf Karim, David P D'Cruz
Nov 30, 2013·Biological Psychiatry·Veerle BerginkHemmo A Drexhage
Dec 29, 2012·Biological Psychiatry·Veerle BerginkHemmo A Drexhage
Dec 14, 2004·Arthritis and Rheumatism·Anu TandonMurray B Urowitz
Mar 1, 2012·Revista clínica española·G Ruiz-IrastorzaUNKNOWN Sociedad Española de Nefrología
Dec 17, 2011·Autoimmunity Reviews·Tai-Ping Lee, Bor-Luen Chiang
Sep 29, 2011·International Journal of Cardiology·James D Fett, Charles F McTiernan
Feb 1, 2011·Clinics in Chest Medicine·N FreymondJ F Cordier
Oct 5, 2010·Néphrologie & thérapeutique·Aicha RadouiNaima Ouzeddoun

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Arthritis and Rheumatism
Murray B UrowitzJ McDonald
Clinics in Rheumatic Diseases
Michael Lockshin
Acta Obstetricia Et Gynecologica Scandinavica
H JulkunenK Teramo
© 2021 Meta ULC. All rights reserved