Increased resistance to acute compression injury in chronically compressed spinal nerve roots. An experimental study

Spine
S KikuchiKjell Olmarker

Abstract

Nerve conduction velocity was studied in the dog cauda equina subjected to chronic and, 1 week later, additional acute compression. To model the situation of spinal stenosis by first inducing a controlled, chronic compression injury and then to add compression at various pressure levels to the already compressed cauda equina. Previous models on nerve root and cauda equina compression have analyzed the effects of compression only on noninjured nerves. Clinically, the nerves that are compressed in spinal stenosis already are exposed to chronic compression. The cauda equine in the lumbar spine of 10 dogs was first compressed by inflating a plastic balloon, which was placed in the spinal canal, to 10 mm Hg with a viscous substance or leaving it noninflated for control. After 1 week, a second plastic balloon, which was welded together with the first balloon, which had been located in the spinal canal for 1 week, was inflated to 50 or 100 mm Hg for 2 hours with 1.5 hour of recovery, and changes in the nerve conduction velocity were analyzed. Before inflation, baseline data, reflecting the effects of the chronic compression per se, were obtained. After 1 week, the nerve conduction velocity was significantly lower in the compressed cau...Continue Reading

References

Mar 1, 1990·Journal of Spinal Disorders·K OlmarkerS Holm
Jan 1, 1989·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·K OlmarkerU Bagge
Mar 15, 1995·Spine·M CornefjordB Rydevik
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Apr 1, 1956·The American Journal of Physiology·S GELFAN, I M TARLOV

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Citations

Nov 10, 2007·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Kazuyuki WatanabeShin-Ichi Kikuchi
Apr 1, 1999·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·P B Massey, G M Kisling
Dec 1, 2004·Journal of Spinal Disorders & Techniques·Akira OndaShinichi Kikuchi
Jan 17, 2008·Spine·Tadashi YonetakeFuminori Kanaya
Feb 27, 2007·Journal of Manipulative and Physiological Therapeutics·Tue Secher JensenCharlotte Leboeuf-Yde
Mar 1, 2005·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Tamaki IgarashiRobert R Myers
Mar 14, 2000·Journal of Manipulative and Physiological Therapeutics·L G Giles
Oct 29, 2004·Journal of Manipulative and Physiological Therapeutics·Anthony V BasteckiJason W Haas
May 30, 1998·Microscopy Research and Technique·M D McGinn, B T Faddis
Jan 23, 2013·Journal of Neural Engineering·A Vanhoestenberghe
Dec 3, 2004·Journal of the Peripheral Nervous System : JPNS·Miho SekiguchiShin-ichi Kikuchi
Jun 15, 1999·Journal of Manipulative and Physiological Therapeutics·D E HarrisonS O Harrison

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