Abstract
Rheumatoid arthritis (RA) is a costly and crippling autoimmune disease that can lead to the development of depression, contributing to suboptimal clinical outcomes. However, no longitudinal studies have identified an association between rheumatoid arthritis and subsequent depression. This study aimed to investigate the incidence and risk factors of depression among RA patients in Taiwan. Using Taiwan's National Health Insurance Research Database, we identified 3,698 newly diagnosed RA patients aged 18 years or older, together with 7,396 subjects without RA matched by sex, age and index date, between 2000 and 2004. The incidence of depression and the risk factors among RA cases were evaluated using Cox proportional-hazard regression. The incidence of depression was 1.74-fold greater in the RA cohort than in the non-RA cohort (11.80 versus 6.89 per 1,000 person-years; p<0.01). Multivariate analysis showed that RA subjects who were female, were older, or had comorbidities such as stroke, chronic kidney disease, or cancer had a significantly greater risk of depression compared with those without these conditions. This population-based cohort study showed a strong relationship between RA and a subsequent risk of depression. The find...Continue Reading
Citations
Feb 10, 2016·Scientific Reports·Ming-Chi LuTzung-Yi Tsai
Sep 6, 2015·The International Journal of Neuropsychopharmacology·Marie FitzgibbonMichelle Roche
Mar 30, 2016·Clinical Rheumatology·Jorge A Zamora-LegoffEric L Matteson
May 26, 2016·Current Psychiatry Reports·Gary J KennedyManuel Fishman
Jun 24, 2016·Clinical Rheumatology·Jorge A Zamora-LegoffCynthia S Crowson
Aug 10, 2016·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Julia DrosselmeyerKarel Kostev
Mar 24, 2016·Revista brasileira de epidemiologia = Brazilian journal of epidemiology·Mariza Miranda Theme FilhaCelia Landmann Szwarcwald
Jan 17, 2017·Expert Review of Pharmacoeconomics & Outcomes Research·Usha SambamoorthiXiaohui Zhao
Feb 14, 2018·Arthritis Care & Research·Ruth Ann MarrieUNKNOWN Canadian Institutes of Health Research Team in Defining the Burden and Managing the Effects of Psychiatric Comorbidity in Ch
Apr 11, 2019·International Journal of Rheumatic Diseases·Hsin-Hua LiTzung-Yi Tsai
Feb 6, 2019·Psychiatry and Clinical Neurosciences·Bogna Grygiel-GórniakMariusz Puszczewicz
Aug 20, 2019·Arthritis Care & Research·Alyssa HowrenMary A De Vera
Dec 12, 2019·Clinical Rheumatology·Khai-Jing NgNing-Sheng Lai
Feb 6, 2020·BMJ Open·Judith SautnerHerwig Pieringer
Aug 6, 2019·Frontiers in Immunology·Chieh-Hsin Lee, Fabrizio Giuliani
Mar 23, 2017·Rheumatology and Therapy·Louis JacobKarel Kostev
Aug 4, 2016·Molecular Medicine Reports·Wen-Juan HuangXia Zhang
Nov 23, 2020·Social Psychiatry and Psychiatric Epidemiology·Chaofu KeYing Wu
Dec 12, 2020·The Annals of Pharmacotherapy·Po-Cheng HouChi-Chuan Wang
Oct 24, 2020·Irish Journal of Medical Science·Songül Bağlan YentürDeran Oskay
Oct 29, 2020·Journal of Family Medicine and Primary Care·Moumita MandalBobby Paul
Feb 2, 2021·Curēus·Sandhya Shri KannayiramEseosa Sanwo
Mar 18, 2021·Advances in Rheumatology·Fernando Henrique Azevedo LopesPedro Felipe Carvalhedo de Bruin
Sep 17, 2021·Advances in Rheumatology·Sara PezzatoSarah Tosato