PMID: 7580706Oct 28, 1995Paper

Increased risk of non-insulin dependent diabetes mellitus at low plasma vitamin E concentrations: a four year follow up study in men

BMJ : British Medical Journal
J T SalonenR Salonen

Abstract

To investigate whether low vitamin E status is a risk factor for incident non-insulin dependent diabetes mellitus. Population based follow up study with diabetes assessed at baseline and at four years. Eastern Finland. Random sample of 944 men aged 42-60 who had no diabetes at the baseline examination. Oral glucose tolerance test at four year follow up. A man was defined diabetic if he had either (a) a fasting blood glucose concentration > or = 6.7 mmol/l, or (b) a blood glucose concentration > or = 10.0 mmol/l two hours after a glucose load, or (c) a clinical diagnosis of diabetes with either dietary, oral, or insulin treatment. 45 men developed diabetes during the follow up period. In a multivariate logistic regression model including the strongest predictors of diabetes, a low lipid standardised plasma vitamin E (below median) concentration was associated with a 3.9-fold (95% confidence interval 1.8-fold to 8.6-fold) risk of incident diabetes. A decrement of 1 mumol/l of uncategorised unstandardised vitamin E concentration was associated with an increment of 22% in the risk of diabetes when allowing for the strongest other risk factors as well as serum low density lipoprotein cholesterol and triglyceride concentrations. Ther...Continue Reading

References

Feb 1, 1979·Biochemical Medicine·Y SatoK Yagi
Oct 1, 1992·Diabetes Research and Clinical Practice·V K MurthyD M Shipp
Nov 17, 1990·BMJ : British Medical Journal·G A Kaplan, J T Salonen
Jun 1, 1981·Biochemical Medicine·I NishigakiK Yagi
Feb 28, 1993·Clinica Chimica Acta; International Journal of Clinical Chemistry·G GallouL Cloarec

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Citations

Feb 6, 2004·BioFactors·N F Wiernsperger
Sep 21, 2007·European Journal of Nutrition·Marc BirringerMichael Ristow
Oct 19, 2006·Current Atherosclerosis Reports·Earl S Ford
Mar 20, 2003·Current Diabetes Reports·Bibi Hasanain, Arshag D Mooradian
Jan 23, 1998·Clinica Chimica Acta; International Journal of Clinical Chemistry·A TavridouK G Alberti
Sep 1, 1997·General Pharmacology·G P BiewengaA Bast
Dec 17, 2005·Antioxidants & Redox Signaling·Asnat Bloch-Damti, Nava Bashan
Jun 10, 2009·Antioxidants & Redox Signaling·Ehab H SarsourPrabhat C Goswami
Jul 7, 2011·Human Molecular Genetics·Jacqueline M MajorDemetrius Albanes
Sep 11, 1998·BMJ : British Medical Journal·J T SalonenK Punnonen
Dec 16, 2004·Journal of Epidemiology and Community Health·M KarpansaloJ T Salonen
Dec 11, 2007·Canadian Journal of Physiology and Pharmacology·Marie-Hélène FraserTimothy Johns
May 1, 2007·Annual Review of Nutrition·Xin Gen LeiJames P McClung
Nov 26, 2008·Journal of Basic and Clinical Physiology and Pharmacology·Swati N TikareKusal K Das
Sep 14, 2012·The Review of Diabetic Studies : RDS·Mariana MureaBarry I Freedman
Feb 4, 2014·International Journal of Environmental Research and Public Health·Yu ZouKeiki Ogino
Jan 28, 2014·Pharmacology & Therapeutics·Karina HuynhRebecca H Ritchie
Sep 7, 2014·Nutrition Journal·Sutapa AgrawalShah Ebrahim
Sep 6, 2012·Nutrition Reviews·Rebecca S Y Wong, Ammu K Radhakrishnan
Sep 13, 2000·American Journal of Public Health·S LiuW C Willett
Oct 24, 2002·Journal of Occupational and Environmental Medicine·Minna KarpansaloJukka T Salonen
May 15, 2007·Clinical and Experimental Hypertension : CHE·Riham Zein Fardoun
Nov 6, 2012·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Bhuvaneshwari SundaramRajat Sandhir
Jan 19, 2016·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Hong XuJuan Jesús Carrero
Mar 24, 2010·Mechanisms of Ageing and Development·Robert Pazdro, John R Burgess
Nov 18, 2008·Metabolism: Clinical and Experimental·Yasuyo AriyamaMasatomo Mori
May 29, 2007·Journal of Ethnopharmacology·Letitia M McCune, Timothy Johns
Aug 30, 2008·The Mount Sinai Journal of Medicine, New York·Alin StirbanDiethelm Tschoepe

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