PMID: 6109856Jan 24, 1981Paper

Increased sensitivity and accuracy of phaeochromocytoma diagnosis achieved by use of plasma-adrenaline estimations and a pentolinium-suppression test

Lancet
M J BrownC T Dollery

Abstract

26 patients with suspected phaeochromocytoma underwent selective venous sampling: a tumour was identified and removed in 18.4 of these patients did not have sustained hypertension, and the only persistent abnormality was an elevated plasma-adrenaline level. The increased plasma-catecholamine concentrations in the tumour patients were not suppressed by pentolinium 2.5 mg i.v., whereas the levels in the 8 non-tumour patients were lowered to the normal range. Calculations based on the arteriovenous differences of adrenaline and noradrenaline suggest that adrenal medullary secretion contributed less than 2% of circulating noradrenaline in the non-tumour patients. Plasma-adrenaline, however, is derived almost entirely from the adrenal gland, and its estimation appears superior to that of noradrenaline in the detection of a small adrenal phaeochromocytoma.

Citations

Jan 1, 1987·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·D LewisS Rigden
Oct 1, 1986·World Journal of Surgery·B E KarlbergT Pollare
Aug 1, 1986·World Journal of Surgery·S GröndalM Telenius-Berg
Aug 31, 1983·Clinica Chimica Acta; International Journal of Clinical Chemistry·D RatgeH Wisser
Sep 24, 1982·European Journal of Pharmacology·M J StevensR F Moulds
Sep 1, 1984·Journal of the Autonomic Nervous System·M EslerG Jennings
Feb 1, 1989·Trends in Pharmacological Sciences·B Max
Jan 1, 1983·General Pharmacology·R F Moulds, M J Stevens
Nov 14, 1981·Lancet·M J Brown, I Macquin
Mar 28, 1981·Lancet
Dec 1, 1984·Lancet·M J Brown, D J Allison
Mar 9, 1985·Lancet
Apr 1, 1993·Baillière's Clinical Endocrinology and Metabolism·V Fonseca, P M Bouloux
Jan 7, 1982·The New England Journal of Medicine
Nov 15, 1984·The New England Journal of Medicine·E L Bravo, R W Gifford
Mar 14, 1985·The New England Journal of Medicine
Dec 3, 1998·Acta Anaesthesiologica Scandinavica·K IritaS Takahashi
Apr 2, 1983·British Medical Journal·D J AllisonJ B Timmis
Jan 31, 1987·British Medical Journal·W M Hague
Sep 16, 1995·BMJ : British Medical Journal·M J Brown
Aug 1, 1983·Postgraduate Medical Journal·M J Brown
Aug 1, 1985·Postgraduate Medical Journal·J F Potter, D G Beevers
May 1, 1994·Postgraduate Medical Journal·F E Karet, M J Brown
Dec 29, 2000·American Journal of Veterinary Research·C BuranakarlK C Bovée
Nov 15, 2006·Annals of the New York Academy of Sciences·Ashley GrossmanGraeme Eisenhofer
Nov 15, 2006·Annals of the New York Academy of Sciences·Morris J BrownDerek S Appleton
Oct 1, 1983·Metabolism: Clinical and Experimental·P D LevinsonA A Kowarski
Sep 28, 2001·British Journal of Anaesthesia·M F James
Feb 14, 1998·The British Journal of Surgery·J G GeogheganJ A Lynn
Nov 1, 1983·Circulation Research·P A Blombery, B G Heinzow
Aug 4, 2007·Clinical Cardiology·Jana SlavíkováOndrej Topolcan
Oct 9, 2007·Journal of Hypertension·Isla S Mackenzie, Morris J Brown

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.