PMID: 6406111Feb 1, 1983Paper

Increased serum concentration of T4-binding globulin in patients with hypogammaglobulinaemia

Clinical Endocrinology
A LeverR L Himsworth

Abstract

Patients with hypogammaglobulinaemia have been regularly found to have abnormal conventional thyroid function test results. The abnormality is due to an increased plasma concentration of T4-binding globulin (TBG). As the prevalence of autoimmune thyroid disease is probably increased in hypogammaglobulinaemia this further abnormality in the plasma proteins may lead to diagnostic confusion. Administration of gammaglobulin by infusion causes a rapid but transient fall in plasma concentrations of TBG and T4 which is probably due to a temporary redistribution of the plasma proteins.

References

Feb 19, 1977·British Medical Journal·W A BurrR Hoffenberg
Aug 1, 1976·The American Journal of Medicine·P E HermansJ D Stobo
Sep 20, 1976·Clinica Chimica Acta; International Journal of Clinical Chemistry·A R BradwellR Hoffenberg
Jul 1, 1968·The Journal of Clinical Endocrinology and Metabolism·C S HollanderJ H Oppenheimer
Sep 20, 1980·Lancet·J S Winter, P J Smail

❮ Previous
Next ❯

Citations

May 1, 1994·Indian Journal of Pediatrics·M F ToppareY Laleli
Dec 1, 1987·The Australian and New Zealand Journal of Psychiatry·P Mitchell
Dec 1, 1983·Journal of Endocrinological Investigation·R Rajatanavin, L E Braverman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Thyroiditis

Autoimmune thyroiditis is an inflammatory disease of thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. Discover the latest research on autoimmune thyroiditis here.