Increased stiffness of the carotid wall material in patients with spontaneous cervical artery dissection

Stroke; a Journal of Cerebral Circulation
David CalvetStéphane Laurent

Abstract

The cause of spontaneous cervical artery dissection (sCAD) is largely unknown. An underlying connective tissue disorder has often been postulated, but arterial mechanical properties have rarely been studied. The study aim was to determine the elastic properties of a cervical artery, the common carotid artery, and a distal muscular artery, the radial artery in sCAD patients. We studied 32 patients with previous sCAD (median delay: 2.2 years) and 32 control subjects with similar age and blood pressure. Internal diameter, intima-media thickness, distensibility, and Young's elastic modulus were determined at the site of the right and left common carotid arteries and the radial artery using noninvasive high-resolution echotracking systems. In patients with previous sCAD, cross-sectional distensibility and compliance of the affected carotid artery did not differ from those of the contralateral carotid artery. Young's elastic modulus (ie, the stiffness of the wall material) was 58% higher (0.44+/-0.32 versus 0.28+/-0.15 kPa.10(3), P<0.001) and circumferential wall stress was 14% higher (56+/-12 versus 49+/-12 kPa, P<0.001) in sCAD patients than in controls. The highest tertile of common carotid artery Young's elastic modulus was assoc...Continue Reading

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Dec 5, 2003·Journal of Hypertension·Pierre BoutouyrieStéphane Laurent
Mar 10, 2004·Circulation·Pierre BoutouyrieStéphane Laurent

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Citations

Apr 25, 2012·Journal of Neurology·Tiina M MetsoAntti J Metso
Oct 30, 2008·The Journal of Laryngology and Otology·A J M Campbell-LloydS Coman
Feb 4, 2012·Cardiology in Review·Raj Ramabhai PatelAmrita Arneja
May 26, 2006·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·G TsivgoulisM Mavrikakis
Feb 27, 2014·Journal of Hypertension·Peter WohlfahrtRenata Cifkova
Mar 1, 2008·Journal of Manipulative and Physiological Therapeutics·André E BussièresCynthia Peterson
Sep 15, 2011·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Claudio BaracchiniRenzo Manara
Sep 13, 2015·La Revue de médecine interne·D Calvet
Nov 25, 2014·Nature Genetics·Stéphanie DebetteUNKNOWN CADISP Group
Feb 1, 2006·Hypertension·Anna PainiStéphane Laurent
Feb 23, 2008·Stroke; a Journal of Cerebral Circulation·Claudio BaracchiniEnzo Ballotta
Mar 30, 2011·Circulation·Stéphanie DebetteUNKNOWN Cervical Artery Dissection and Ischemic Stroke Patients (CADISP) Group
Jun 4, 2005·Stroke; a Journal of Cerebral Circulation·Sidney M RubinsteinScott Haldeman
Oct 31, 2019·The Journal of Manual & Manipulative Therapy·Lucy Caroline ThomasGail Durbridge

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