Increased urinary cortisol levels during the menopausal transition

Menopause : the Journal of the North American Menopause Society
Nancy Fugate WoodsEllen Sullivan Mitchell

Abstract

To determine whether cortisol levels change prospectively during the menopausal transition (MT); whether these changes are associated with changes in the hypothalamic-pituitary-ovarian axis (follicle-stimulating hormone [FSH] and estrone glucuronide [E1G]), stressors, or menopause symptoms; and whether women who experienced a rise in cortisol levels during the transition had behavioral practices, stressors, vasomotor symptoms, or mood or sleep disturbances that affected hypothalamic-pituitary-adrenal axis function. One hundred sixty-nine women in the middle or late MT or early postmenopause stages provided monthly urine specimens for cortisol, FSH, and E1G, and rated symptoms and stress levels as part of a longitudinal study of the MT. Of these women, 91 completed a transition to the next MT stage: from early to middle (n = 30), middle to late (n = 39), or late to postmenopause (n = 22) and were eligible for inclusion in the analyses. Cortisol increased from 7 to 12 months before the late MT stage to 7 to 12 months after onset of the late MT stage. There were no differences before and after the middle MT stage or the final menstrual period. Women with increased cortisol (>10 ng/mg creatinine) during the late MT stage had more s...Continue Reading

References

Feb 1, 1987·Journal of Behavioral Medicine·P J BrantleyN B Rappaport
Feb 1, 1973·The Journal of Clinical Endocrinology and Metabolism·J M GrodinP C MacDonald
Jun 15, 1980·American Journal of Obstetrics and Gynecology·F Z StanczykU Goebelsmann
Nov 1, 1995·Annals of Internal Medicine·E T PoehlmanA W Gardner
Feb 1, 1997·Seminars in Reproductive Endocrinology·L D Dorn, G P Chrousos
Feb 10, 1999·Experimental Gerontology·S S Yen, G A Laughlin
Jul 15, 1999·Journal of the American Geriatrics Society·G A GreendaleT E Seeman
Sep 19, 2000·Menopause : the Journal of the North American Menopause Society·E S MitchellA Mariella
Dec 29, 2000·Journal of the American Geriatrics Society·G A GreendaleE Barrett-Connor
Oct 9, 2001·Climacteric : the Journal of the International Menopause Society·N E AvisC Longcope
May 22, 2002·Psychosomatic Medicine·Lynda H PowellMarcia G Ory
Aug 6, 2002·The Journal of Clinical Endocrinology and Metabolism·Bill L LasleyMary Fran Sowers
Oct 18, 2002·Psychoneuroendocrinology·P J SchmidtL St Clair
Apr 8, 2003·The Journal of Clinical Endocrinology and Metabolism·John F RandolphBill L Lasley
Jun 6, 2003·The Journal of Clinical Endocrinology and Metabolism·Molly C Carr
Oct 6, 2004·Journal of Immunoassay & Immunochemistry·Kathleen A O'ConnorMark S Handcock

❮ Previous
Next ❯

Citations

Jan 17, 2007·Menopause : the Journal of the North American Menopause Society·Steriani Elavsky, Edward McAuley
Jan 8, 2008·Menopause : the Journal of the North American Menopause Society·Nancy Fugate WoodsSullivan Mitchell
Jun 20, 2008·Menopause : the Journal of the North American Menopause Society·Pauline M MakiStacie E Geller
Aug 30, 2008·Menopause : the Journal of the North American Menopause Society·Nancy Fugate WoodsKathleen Smith-DiJulio
Mar 27, 2009·Menopause : the Journal of the North American Menopause Society·Nancy Fugate WoodsKathleen Smith-Dijulio
Jul 16, 2010·Menopause : the Journal of the North American Menopause Society·Lori CrayEllen Sullivan Mitchell
Nov 3, 2010·Menopause : the Journal of the North American Menopause Society·Angelo CagnacciAnnibale Volpe
Jan 19, 2011·Menopause : the Journal of the North American Menopause Society·Myra S Hunter
Oct 5, 2011·Menopause : the Journal of the North American Menopause Society·Jeannette M PainovichC Noel Bairey Merz
Aug 5, 2008·Clinical Obstetrics and Gynecology·Nanette Santoro
May 2, 2014·Menopause : the Journal of the North American Menopause Society·Nancy Fugate WoodsJerald R Herting
Sep 14, 2010·Journal of Women's Health·Ayelet Ziv-Gal, Jodi A Flaws
Apr 25, 2007·Climacteric : the Journal of the International Menopause Society·A R GenazzaniT Simoncini
Apr 29, 2011·Climacteric : the Journal of the International Menopause Society·E S Mitchell, N F Woods
Oct 4, 2011·Obstetrics and Gynecology Clinics of North America·Gail A GreendalePauline M Maki
Feb 8, 2011·Maturitas·Päivi Polo-Kantola
Oct 2, 2007·Maturitas·Kathleen Smith-DiJulioEllen Sullivan Mitchell
Sep 30, 2010·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Carolyn J CrandallGail A Greendale
Dec 15, 2015·Clinical Endocrinology·S D ReedK A Guthrie
Jan 22, 2015·Menopause : the Journal of the North American Menopause Society·Anne-Josée GuimondJosée Savard
Mar 24, 2015·Social Science & Medicine·Lindsay Till Hoyt, April M Falconi
Apr 10, 2016·Clinical Endocrinology·Carolyn J GibsonKaren A Matthews
Jan 31, 2018·Menopause : the Journal of the North American Menopause Society·Nini G L CallanNancy F Woods
Feb 3, 2018·Nature Reviews. Endocrinology·Patrizia MonteleoneTommaso Simoncini
Feb 6, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Sébastien FournierRichard Kinkead
Dec 31, 2019·PloS One·Ruither O G CarolinoJanete Anselmo-Franci
Jan 9, 2020·Menopause : the Journal of the North American Menopause Society·Pauline M MakiRhoda J Conant
Feb 16, 2019·Women's Midlife Health·Linda M Gerber, Lynnette Leidy Sievert
Feb 16, 2019·Women's Midlife Health·Lynnette Leidy SievertDaniel E Brown
Oct 20, 2020·Frontiers in Neurology·Pauline M Maki, Rebecca C Thurston
Dec 17, 2020·Menopause : the Journal of the North American Menopause Society·Margo D NathanHadine Joffe
Apr 27, 2021·Journal of Neuroendocrinology·Adesina Paul ArikaweJanete Anselmo-Franci
Oct 13, 2021·Menopause : the Journal of the North American Menopause Society·Angelo CagnacciFederica Palma

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.