PMID: 3761089Oct 1, 1986Paper

Increased urinary excretion of inorganic sulfate in premature infants fed bovine milk protein

The Journal of Pediatrics
F R GreerJ Loker

Abstract

We report measurements of urinary inorganic sulfate (iSO4) in 38 very low birth weight (VLBW) premature infants receiving various protein intakes in the first 2 months of life. The primary source of urinary iSO4 is the metabolism of amino acids containing sulfur (methionine, cysteine, taurine). It was hypothesized that urinary iSO4 excretion would be increased in VLBW infants fed the relatively high concentrations of protein in mother's own milk (HM), mother's own milk fortified with 0.85 gm/dl bovine whey (fortified HM), and a special formula for premature infants (Similac Special Care, 20 cal/oz), and that urinary iSO4 excretion would correlate with calcium excretion. VLBW premature infants fed HM (protein intake 3.3 gm/kg day) excreted very small amounts of urinary iSO4 compared with infants fed fortified HM (4.5 gm/kg/day protein), Similac SC (2.9 gm/kg/day protein), or Similac (2.7 gm/kg/day protein), all three of which contain bovine whey. Unlike the case in adults, there was no correlation between either total protein intake and urinary calcium excretion or urinary iSO4 excretion. There was, however, a significant correlation between methionine intake and urinary iSO4 excretion (r = 0.48). We speculate that increased uri...Continue Reading

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Citations

Jun 23, 2018·The Cochrane Database of Systematic Reviews·Emma A AmissahJane E Harding
Sep 13, 2000·Critical Reviews in Clinical Laboratory Sciences·D E Cole, J Evrovski
Mar 4, 2006·The British Journal of Nutrition·Maurice J Arnaud
Sep 24, 2020·The Cochrane Database of Systematic Reviews·Emma A AmissahJane E Harding

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