Increased yields and simplified purification with a second-generation cobalt catalyst for the oxidative formation of trans-THF rings

Organic Letters
Cory PalmerBrian L Pagenkopf

Abstract

The synthesis of a second-generation cobalt catalyst for the formation of trans-THF products via the Mukaiyama aerobic oxidative cyclization is reported. Two procedures have been developed with the new water-soluble catalyst that give superior yields and greatly simplify purification compared to the previous catalysts.

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Citations

Jun 23, 2012·Journal of the American Chemical Society·Yan MillerSherry R Chemler
Mar 16, 2016·Journal of the American Chemical Society·Gustavo M Borrajo CallejaClément Mazet
Nov 5, 2016·The Journal of Organic Chemistry·Shunya TakahashiHiroyuki Koshino
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Aug 29, 2018·Angewandte Chemie·Marc HeinrichAlois Fürstner
Nov 11, 2016·Beilstein Journal of Organic Chemistry·Juliane AdrianChristian B W Stark
Apr 24, 2013·Angewandte Chemie·Gaëlle ValotAlois Fürstner
Jun 15, 2021·Organic Letters·Zulema Peralta-Neel, K A Woerpel
Jun 25, 2021·Chemical Science·Shota KatoHaruhiko Fuwa
Jan 25, 2011·Organic Letters·Nicholas A Morra, Brian L Pagenkopf
Mar 27, 2012·The Journal of Organic Chemistry·Luiz C Dias, Marco A B Ferreira
May 3, 2019·The Journal of Organic Chemistry·Jonathan P Oswald, K A Woerpel
May 10, 2020·Organic Letters·David R WilliamsDavid Rodríguez-Reyes
Apr 24, 2014·The Journal of Organic Chemistry·Gabrielle J DugasIsaac J Krauss
Jan 9, 2019·Organic Letters·Fumihiko YoshimuraKeiji Tanino

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