PMID: 7512684Apr 1, 1994Paper

Increases in chromosome aberrations and in abnormal sperm morphology in rubber factory workers

Mutation Research
A RendónI Pineda

Abstract

Subjects working at a rubber plant in a chemicals warehouse or in calandering and bambury units were analyzed for both sperm parameters and structural chromosome aberrations in peripheral blood lymphocytes. Sperm analysis was performed in a group of 24 workers for comparison with fertile (n = 24) and infertile (n = 24) control groups. The statistical analyses of semen volume, vitality and sperm count did not show significant differences between exposed and fertile groups but significant differences were found from the infertile group. A significantly lower proportion of normal sperm head shapes was found in exposed subjects when compared to the fertile group (40.1 vs. 57.8). Seven exposed workers were re-analyzed 1 year later and their sperm parameters did not change. The cytogenetic analysis showed a significant increase (3.90%) in the percentage of cells with aberrations in bambury workers (n = 11). However, no differences were found between calandering workers (n = 8) and control subjects (n = 10). Workplace air samples taken on the day of tissue sampling did not show any increase above the Cuban maximal allowed concentration for benzo[a]pyrene or toluene.

References

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Citations

Oct 24, 2002·Teratogenesis, Carcinogenesis, and Mutagenesis·Mehmet TopaktaşAhmet Kayraldiz
Apr 12, 2008·International Archives of Occupational and Environmental Health·Kristina Jakobsson, Zoli Mikoczy
Oct 12, 2000·Mutation Research·C Q ZhuY H Chen
Sep 3, 1999·Occupational and Environmental Medicine·A Plenge-Bönig, W Karmaus
Oct 6, 2017·Human Reproduction Update·Hagai LevineShanna H Swan
Feb 18, 2021·Toxicology and Industrial Health·Dicky Faizal IrnandiRina Yudiwati

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