Increasing diversion of methadone in Vancouver, Canada, 2005-2015

Journal of Substance Abuse Treatment
Hudson ReddonKanna Hayashi

Abstract

Although methadone, an opioid agonist, has been an effective medication used to treat opioid use disorder for over 40years, recent studies have found that methadone was identified in more than a quarter of prescription opioid-related deaths among people who use illicit drugs in Vancouver, Canada. Thus, we sought to longitudinally examine the availability of diverted methadone among people who inject drugs (PWID). Data were collected from three prospective cohorts of PWID in Vancouver, Canada between December 2005 and May 2015. Multivariable generalized estimating equation logistic regression was used to identify temporal trends in the immediate availability of diverted methadone (defined as the ability to acquire illicit methadone in <10min). A total of 2092 participants, including 727 (34.8%) women, were included in the present study. In the multivariable analyses after adjusting for a range of potential confounders, later calendar year (adjusted odds ratio [AOR]=1.21 per year; 95% confidence interval [CI]: 1.19-1.23) was independently and positively associated with reporting immediate availability of diverted methadone. We observed a significant increase in the reported availability of diverted methadone among PWID over a ten...Continue Reading

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Citations

May 30, 2019·Drug Testing and Analysis·Terhi N KeltanenIlkka A Ojanperä
Oct 15, 2019·Substance Use & Misuse·Johnathan K ZhaoRicky N Bluthenthal
Mar 7, 2021·Substance Abuse Treatment, Prevention, and Policy·Eugenia Oviedo-JoekesKelli Harper
Jun 24, 2020·Peptides·Richard J Bodnar

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