PMID: 2497306May 15, 1989Paper

Increasing the survival of extremely-immature (24- to 28-weeks' gestation) infants--at what cost?

The Medical Journal of Australia
L W DoyleW H Kitchen

Abstract

In one tertiary perinatal centre, the advent of positive-pressure assisted ventilation in the 1970s improved the survival of neonates of 24 to 28 completed weeks of gestation. However, the rate of increase in the resources for assisted ventilation and the improvements in survival rates were stepwise and not smooth. Consequently, it has been possible to calculate the cost-effectiveness of neonatal intensive care up to the time of hospital discharge over two separate eras of stable consumption of resources for assisted ventilation. During 1977-1983, to produce one survivor at 24-weeks' gestation compared with one at 28-weeks' gestation consumed 14.4-times the number of patient-days of assisted ventilation, and 4.9-times more of the total nursery resources; the cost-effectiveness of intensive care during this period decreased with decreasing maturity. The over-all cost-effectiveness up to the time of hospital discharge for infants of 24- to 28-weeks' gestation during 1977-1983, compared with 1971-1974, when assisted ventilation was rare, was $62,268 per additional survivor. After 1983, the consumption of resources for assisted ventilation more than doubled in infants of 24- to 28-weeks' gestation. However, there was a diminishing ...Continue Reading

References

Aug 1, 1987·The Australian & New Zealand Journal of Obstetrics & Gynaecology·L W DoyleW H Kitchen
Jun 2, 1983·The New England Journal of Medicine·M H BoyleS P Horwood

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Citations

Feb 1, 1990·The Australian & New Zealand Journal of Obstetrics & Gynaecology·L W Doyle
Jul 19, 1993·The Medical Journal of Australia·J D Vince
Apr 1, 1996·Journal of Paediatrics and Child Health·L W DoyleE Bowman
Jun 1, 1995·The Journal of Legal Medicine·R H Blank
Jan 1, 1995·Sozial- Und Präventivmedizin·M Mugford
Jan 1, 1996·International Journal of Technology Assessment in Health Care·B KhoshnoodB I Kim
Jan 1, 1994·Human Nature : an Interdisciplinary Biosocial Perspective·Linda S Siegel
Oct 1, 1990·Journal of Paediatrics and Child Health·E ThambapillaiL J Murton
Aug 3, 1992·The Medical Journal of Australia·W H KitchenC Callanan
Feb 26, 2016·Pediatrics·Dmitry DukhovnyJohn A F Zupancic
Mar 3, 2004·Pediatrics·Lex W Doyle, UNKNOWN Victorian Infant Collaborative Study Group

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