Increasing varicella incidence rates among children in the Republic of Korea: an age-period-cohort analysis

Epidemiology and Infection
Young Hwa LeeJong-Koo Lee

Abstract

In the Republic of Korea, despite the introduction of one-dose universal varicella vaccination in 2005 and achieving a high coverage rate of 98.9% in 2012, the incidence rate has been increased sevenfold. This study aimed to investigate time trends of varicella incidence rate, assessing the age, period and birth cohort effects. We used national data on the annual number of reported cases from 2006 to 2017. A log-linear Poisson regression model was used to estimate age-period-cohort effects on varicella incidence rate. From 2006 to 2017, the incidence of varicella increased from 22.5 cases to more than 154.8 cases per 100 000. Peak incidence has shifted from 4 to 6 years old. The estimated period and cohort effects showed significant upward patterns, with a linear increasing trend by net drift. There has been an increase in the incidence among the Korean population regarding period and cohort despite the universal vaccination of varicella vaccine. Our data suggest the need for additional studies to address the current gap in herd immunity.

References

Jan 1, 1992·Statistical Methods in Medical Research·T R Holford
Jun 1, 1987·Statistics in Medicine·D Clayton, E Schifflers
Jun 1, 1987·Statistics in Medicine·D Clayton, E Schifflers
Oct 1, 1994·International Journal of Epidemiology·A VerdecchiaS Mariotti
Feb 8, 2000·International Journal of Epidemiology·H HouwelingM J Sprenger
Mar 29, 2001·The New England Journal of Medicine·M VázquezE D Shapiro
May 8, 2002·American Journal of Epidemiology·Marie-Pierre PréziosiFrançois Simondon
Feb 19, 2004·JAMA : the Journal of the American Medical Association·Marietta VázquezEugene D Shapiro
May 3, 2008·The Journal of Infectious Diseases·Catherine Sadzot-DelvauxStanley A Plotkin
Apr 13, 2010·The Journal of Infection·So Hee KimEun Hwa Choi
Oct 29, 2010·Journal of Medical Virology·Won Suk ChoiHee Jin Cheong
May 26, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Philip S Rosenberg, William F Anderson
Feb 13, 2013·Journal of Korean Medical Science·Hyunju LeeKyung-Hyo Kim
Jul 11, 2013·The Pediatric Infectious Disease Journal·Paolo BonanniPeter Wutzler
Sep 10, 2013·Journal of Korean Medical Science·Young June ChoeHoan Jong Lee
Mar 29, 2014·Clinical and Vaccine Immunology : CVI·Sung Hee OhShin Ah Kim
Aug 26, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Philip S RosenbergWilliam F Anderson
Nov 26, 2014·Epidemiology and Health·Sunhee Park, Eunhee Cho
Aug 4, 2016·Human Vaccines & Immunotherapeutics·Ui Yoon ChoiJin Han Kang
Dec 21, 2017·Emerging Infectious Diseases·Jong-Hun Kim, Hae-Kwan Cheong
Mar 20, 2019·Journal of Korean Medical Science·Young Hwa LeeJong-Koo Lee

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Citations

Jul 3, 2021·International Journal of Environmental Research and Public Health·Da Hae KimJin Hee Kim
Jul 14, 2021·Journal of Korean Medical Science·BongKyoo ChoiSang Baek Koh
Nov 6, 2021·Journal of Medical Virology·Young Hwa LeeSung-Il Cho

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