Incremental predictive value of myocardial scintigraphy with 123I-BMIPP in patients with acute myocardial infarction treated with primary percutaneous coronary intervention

European Journal of Nuclear Medicine and Molecular Imaging
Mamoru NanasatoToyoaki Murohara

Abstract

It is unclear whether 123I-labelled beta-methyl iodophenyl pentadecanoic acid (123I-BMIPP) myocardial scintigraphy adds further predictive value for future cardiac events compared with the variables obtained during cardiac catheterisation in patients with acute myocardial infarction (AMI) treated with primary percutaneous coronary intervention (PCI). We therefore investigated whether 123I-BMIPP imaging in patients with AMI treated by primary PCI was useful in predicting future cardiac events. One hundred and fifty-nine patients with AMI who were treated with primary PCI and underwent left ventriculography (LVG) on admission underwent 201Tl and 123I-BMIPP myocardial scintigraphy. Scintigrams were visually classified, and the total defect score (TDS) was calculated. Major adverse cardiac events (MACE) were defined as cardiac death including sudden death, congestive heart failure and recurrence of acute coronary syndrome. Patients were followed up for a mean of 34.5 months (12-63 months). Twenty-six patients had MACE. Kaplan-Meier analysis indicated that patients with the top 50% of 123I-BMIPP TDSs had a significantly higher rate of MACE (P=0.007). Patients with mismatch between 201Tl and 123I-BMIPP images also had significantly m...Continue Reading

References

May 1, 1995·Journal of the American College of Cardiology·J J MahmarianM S Verani
May 20, 1998·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·S FujiwaraH Tomoike
Nov 18, 2000·European Journal of Nuclear Medicine·A S HambÿeP Franken
Jun 23, 2001·The New England Journal of Medicine·G MontalescotUNKNOWN ADMIRAL Investigators. Abciximab before Direct Angioplasty and Stenting in Myocardial Infarction Regarding Acute and Long-Te
May 3, 2002·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Manuel D CerqueiraUNKNOWN American Heart Association Writing Group on Myocardial Segmentation and Registration for Cardiac Imaging

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Citations

Nov 6, 2008·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Masato Nishimura, Toshihiko Ono
May 5, 2007·European Journal of Nuclear Medicine and Molecular Imaging·Junichi Taki, Ichiro Matsunari
Oct 24, 2009·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Yoichi Inaba, Steven R Bergmann
Nov 18, 2010·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Nagara Tamaki, Keiichiro Yoshinaga
Feb 6, 2007·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Taishiro ChikamoriTsunehiko Nishimura
Jun 30, 2007·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Nagara TamakiYuko Kawai
Jan 15, 2008·Journal of the American College of Cardiology·Masato NishimuraToshihiko Ono
Dec 14, 2019·Journal of the American Heart Association·Aitor UribarriUNKNOWN RETAKO Investigators
Apr 6, 2016·Texas Heart Institute Journal·Gwendolyn Rose DerkLeigh C Reardon
Aug 26, 2017·Heart·Ken KatoChristian Templin
Mar 18, 2021·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Atsushi YamamotoNobuhisa Hagiwara
Feb 19, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Masakazu YamagishiUNKNOWN Japanese Circulation Society Working Group
Nov 26, 2021·Annals of Nuclear Medicine·Motoko MorishimaYosuke Ishii

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