Incremental prognostic factors associated with cow's milk allergy outcomes in infant and child referrals: the Milan Cow's Milk Allergy Cohort study

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Alessandro FiocchiPatrizia Restani

Abstract

The prognosis for many children with cow's milk allergy (CMA) is remission within 3 years, and the clinical parameters that predict duration of disease have not been measured incrementally. To prospectively determine prognostic predictors of tolerance in a random cohort of referrals using CMA workup outcomes as covariates and tolerance as the status variable in a duration model of CMA. The 2001-2006 Milan Cow's Milk Allergy Cohort (MiCMAC) enrolled children referrals using double-blind, placebo-controlled food challenges (DBPCFCs) as study end points (confirmation of CMA; onset of tolerance). The Cox regression model was used to analyze all clinical factors that contributed to tolerance. Covariates analyzed were skin, gastrointestinal, and respiratory symptoms; history and demographics at presentation; age at diagnosis and DBPCFC outcomes; sensitization (skin and serum) by cow's milk protein fractions; sensitization to other food and inhalant allergens; total IgE levels; specific IgE concentrations for cow's milk protein fractions, other ingestants, and aeroallergens; and threshold doses at DBPCFC. Sensitization and DBPCFC were performed at 6-month intervals. A total of 112 infants were enrolled (mean [SD] age, 13.85 [9.84] mon...Continue Reading

References

Jul 1, 1989·The Journal of Pediatrics·H A Sampson, S M Scanlon
Jan 1, 1994·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·A Høst
Feb 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·D J HillC S Hosking
Apr 15, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S H Sicherer, H A Sampson
Aug 29, 2000·Archives of Disease in Childhood·J Salazar-de-Sousa
Jun 23, 2001·Allergologia et immunopathologia·A M Plaza MartínJ I Sierra Martínez
Sep 1, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P ChatchateeH A Sampson
Sep 12, 2001·Allergy·S G JohanssonUNKNOWN EAACI (the European Academy of Allergology and Cinical Immunology) nomenclature task force
Oct 23, 2002·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Thomas L Diepgen, UNKNOWN Early Treatment of the Atopic Child Study Group
Dec 19, 2002·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Alessandro FiocchiLuigi Terracciano
Aug 5, 2003·Pediatrics·Alessandro FiocchiRenato Valsasina
Jan 1, 2004·Journal of the American Dietetic Association·Ronette R BriefelBarbara Devaney
Feb 5, 2004·The Journal of Pediatrics·Timo VantoPertti Koskinen
Jun 11, 2004·Acta Paediatrica·M GiovanniniC Agostoni
Jun 16, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M C García-AraM Martín-Esteban
Aug 19, 2004·The Journal of Allergy and Clinical Immunology·Lynette P C ShekHugh A Sampson
Jun 4, 2005·Allergy·A MartelliA Fiocchi
Oct 8, 2005·The Journal of Allergy and Clinical Immunology·Kristiina M SaarinenErkki Savilahti
Apr 12, 2006·Allergologia et immunopathologia·Antonio MartorellMargarita Fernández
Aug 9, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Ramesh J KurukulaaratchyS Hasan Arshad
Sep 5, 2006·Allergy and Asthma Proceedings·Alessandro FiocchiAlberto Martelli
Feb 16, 2007·Pediatric Dermatology·J L SinagraB Capitanio
Jun 15, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Y LevyY L Danon
Oct 16, 2007·The Journal of Allergy and Clinical Immunology·Justin M SkripakRobert A Wood

❮ Previous
Next ❯

Citations

Aug 1, 2012·Current Allergy and Asthma Reports·Faith Huang, Jennifer S Kim
Feb 13, 2013·Current Opinion in Allergy and Clinical Immunology·Alessandro FiocchiRichard W Weber
Feb 4, 2016·The World Allergy Organization Journal·Thanh D DangKatrina J Allen
Jan 17, 2012·Immunology and Allergy Clinics of North America·Antonella Cianferoni, Antonella Muraro
Oct 31, 2012·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K M Järvinen, J Celestin
May 23, 2013·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Giovanni B PajnoGiovanni Passalacqua
Oct 12, 2013·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Christophe Dupont
Jan 3, 2013·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M Vázquez-OrtizA M Plaza-Martín
Sep 11, 2012·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Emma M Savilahti, Erkki Savilahti
Jan 14, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L TerraccianoA Fiocchi
Mar 5, 2014·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·D LuytA T Clark
Mar 1, 2012·The Journal of Allergy and Clinical Immunology·A Wesley BurksHugh A Sampson
Mar 5, 2013·The Journal of Allergy and Clinical Immunology·Jonathan M Spergel
Jan 1, 2013·The Journal of Allergy and Clinical Immunology·Robert A WoodHugh A Sampson
Dec 8, 2010·The Journal of Allergy and Clinical Immunology·Alessandro FiocchiRichard F Lockey
Apr 7, 2012·The Journal of Pediatrics·Arnon ElizurYitzhak Katz
May 1, 2010·Current Opinion in Allergy and Clinical Immunology·Susan L PrescottAlessandro Fiocchi
Apr 14, 2012·Current Opinion in Allergy and Clinical Immunology·Giovanni PassalacquaGiovanni B Pajno
Nov 9, 2016·Allergy, Asthma & Immunology Research·Laura PerezábadIván López-Expósito
Jan 15, 2014·Expert Review of Clinical Immunology·Christophe Dupont
Mar 31, 2018·Current Opinion in Allergy and Clinical Immunology·Lamia DahdahMaurizio Mennini
Apr 5, 2017·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Valentina PecoraAlessandro Fiocchi
Feb 29, 2020·Immunity, Inflammation and Disease·Vincenzo FierroJesus Jiménez
Apr 7, 2020·Current Opinion in Allergy and Clinical Immunology·Enza D'Auria, Carina Venter
Feb 26, 2019·Frontiers in Pediatrics·Stefania ArasiAlessandro G Fiocchi
Aug 14, 2019·Medicina·Arianna GiannettiGiampaolo Ricci
Mar 6, 2021·The World Allergy Organization Journal·Alessandro FiocchiMaurizio Mennini
Apr 14, 2019·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·A BocquetUNKNOWN Committee on Nutrition of the French Society of Pediatrics (CNSFP)
May 6, 2021·Nutrients·Arianna GiannettiAndrea Pession
May 1, 2010·Current Opinion in Allergy and Clinical Immunology
Dec 8, 2021·Immunity, Inflammation and Disease·Katy SorensenRebecca J Stratton

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

The Journal of Allergy and Clinical Immunology
Marco H K HoKatrina J Allen
Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
P MeglioElena Galli
The Journal of Allergy and Clinical Immunology
Satya D NarisetyRobert A Wood
The Journal of Allergy and Clinical Immunology
Justin M SkripakRobert A Wood
© 2022 Meta ULC. All rights reserved