Incremental prognostic value of quantitative plaque assessment in coronary CT angiography during 5 years of follow up

Journal of Cardiovascular Computed Tomography
Jonathan NadjiriMartin Hadamitzky

Abstract

We sought to assess the incremental prognostic value of quantitative plaque characterization beyond established CT risk scores. Several plaque characteristics detectable by coronary computed tomographic angiography (coronary CTA) are thought to be indicative of vulnerable plaques and subsequent cardiac events, particularly low attenuation plaque volume (LAPV), positive remodeling and the napkin-ring sign which is high density vascular adhesion with a small center of low density. It is unknown how quantitative plaque assessment can contribute to the long-term prediction of cardiovascular events in relation to established CT risk scores such as the calcium score or Segment Stenosis Score (SSS). In 1168 consecutive patients with suspected coronary artery disease (CAD), calcium score measurement and coronary plaque characterization was performed comprising the presence of calcified, non-calcified, and partially calcified plaques on a per-segment basis. In all non-calcified or partially calcified plaques, semi-automated plaque analysis was performed to quantify low attenuation plaque volume (density <30 HU), total non-calcified plaque volume (<150 HU, TNCPV) and remodeling index. The presence of the napkin-ring sign was assessed vis...Continue Reading

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Citations

Aug 16, 2016·Journal of Cardiovascular Computed Tomography·Christian TescheU Joseph Schoepf
Jul 28, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Shinie Kuo, Kavitha M Chinnaiyan
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Oct 4, 2019·European Heart Journal Cardiovascular Imaging·Tom FinckMartin Hadamitzky
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