PMID: 6411932Jul 1, 1983Paper

Indentations in the terminal cisternae of amphibian and mammalian skeletal muscle fibers

Journal of Ultrastructure Research
A F Dulhunty, A A Valois

Abstract

Indentations (hillocks and dimples) in the terminal cisternae of mammalian and amphibian skeletal muscle fibers were studied using freeze-fracture and serial thin-section techniques. The structures were seen in all muscles and had a regular separation from each other and from the T-tubule. Indentations were smaller than fenestrations and formed concavities in, but not macromolecular pores through, the terminal cisternae. The average numbers of indentations in rat muscles (measured along the length of the terminal cisternae, within 150 nm of the triadic junction) varied from 0.9 per micrometer in soleus fibers to 9.6 per micrometer in posterior cricoarytenoid fibers. The average numbers in amphibian sartorius fibers varied from 1.6 to 3.6 per micrometer in muscles from different species. The regular alignment of the indentations along the triad, as well as a close correlation between their numbers and the contractile properties of the muscle, suggest that they function in contractile activation and may represent sites of calcium release from the terminal cisternae.

References

Sep 1, 1979·The American Journal of Anatomy·A F Dulhunty, M Dlutowski
Jan 1, 1976·The Journal of Physiology·W K ChandlerM F Schneider
Mar 1, 1975·Journal of Ultrastructure Research·D G RaynsC L Sutherland
May 1, 1975·Journal of Ultrastructure Research·B R Eisenberg, A M Kuda
Jan 1, 1976·Journal of Ultrastructure Research·B R Eisenberg, A M Kuda
Mar 1, 1974·The Journal of Cell Biology·B R EisenbergJ B Peter
May 1, 1980·Journal of Ultrastructure Research·J R SommerJ Junker
Dec 1, 1981·The Journal of Physiology·S Hollingworth, M W Marshall
Jul 1, 1982·Muscle & Nerve·A Dulhunty, A Valois
Aug 1, 1981·The Australian Journal of Experimental Biology and Medical Science·D F DaveyS Y Wong
Apr 10, 1980·Nature·F EusebiT Takahashi
May 25, 1958·The Journal of Biophysical and Biochemical Cytology·L D PEACHEY

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Citations

Jan 1, 1985·Progress in Biophysics and Molecular Biology·J CailléO Rougier
Jan 1, 1992·Progress in Biophysics and Molecular Biology·A F Dulhunty
Apr 1, 1995·Progress in Neurobiology·L Larsson, T Ansved
Jul 1, 1987·The Journal of Cell Biology·C Franzini-ArmstrongE Varriano-Marston
Sep 1, 1990·Baillière's Clinical Endocrinology and Metabolism·R FrischknechtG Vrbová
Oct 1, 1993·Baillière's Clinical Endocrinology and Metabolism·W T Garvey, M J Birnbaum
Nov 15, 2018·Physiological Reviews·Lars LarssonMarco Sandri
Nov 1, 1987·Muscle & Nerve·A F Dulhunty

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