Independence of landmark and self-motion-guided navigation: a different role for grid cells

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
Bruno PoucetRobert U Muller

Abstract

Recent interest in the neural bases of spatial navigation stems from the discovery of neuronal populations with strong, specific spatial signals. The regular firing field arrays of medial entorhinal grid cells suggest that they may provide place cells with distance information extracted from the animal's self-motion, a notion we critically review by citing new contrary evidence. Next, we question the idea that grid cells provide a rigid distance metric. We also discuss evidence that normal navigation is possible using only landmarks, without self-motion signals. We then propose a model that supposes that information flow in the navigational system changes between light and dark conditions. We assume that the true map-like representation is hippocampal and argue that grid cells have a crucial navigational role only in the dark. In this view, their activity in the light is predominantly shaped by landmarks rather than self-motion information, and so follows place cell activity; in the dark, their activity is determined by self-motion cues and controls place cell activity. A corollary is that place cell activity in the light depends on non-grid cells in ventral medial entorhinal cortex. We conclude that analysing navigational syst...Continue Reading

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Citations

Apr 24, 2015·Frontiers in Neurorobotics·Adrien JauffretPhilippe Gaussier
Jun 14, 2014·Frontiers in Integrative Neuroscience·Pierre-Yves JacobFrancesca Sargolini
Jun 9, 2016·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Andrew Glennerster
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Nov 19, 2015·Frontiers in Behavioral Neuroscience·Bruno PoucetVincent Hok
Feb 8, 2019·The Journal of Experimental Biology·Philippe GaussierBruno Poucet
Sep 5, 2018·ELife·Andrej Bicanski, Neil Burgess
Aug 14, 2019·Journal of Neuroscience Methods·M L MachadoS Besnard

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