Independent and combined associations of physical fitness components with inflammatory biomarkers in children and adolescents

Pediatric Research
Alvaro Delgado-AlfonsoUP&DOWN Study Group.

Abstract

We aimed to examine the independent and combined associations of cardiorespiratory fitness, muscular fitness, and motor ability with single and clustered inflammatory biomarkers in children and adolescents. This study included 503 children and adolescents. Cardiorespiratory fitness, upper- and lower-muscular fitness, and motor ability were assessed using field-based tests. Fasting blood samples were obtained to determine the levels of a set of inflammatory biomarkers. Global physical fitness and clustered inflammatory biomarker scores were computed. Associations between physical fitness and inflammatory biomarkers were analyzed through linear regression. Differences in inflammatory biomarker levels between physical fitness tertiles were tested. Global physical fitness was inversely associated with single and clustered inflammatory biomarkers in children (p < 0.05); and with C-reactive protein, complement factor C4, leptin, and clustered inflammatory biomarkers in adolescents (p < 0.025). Cardiorespiratory fitness and upper-muscular fitness were negatively and independently associated with several single and clustered inflammatory biomarkers in children and adolescents (p < 0.05). Differences were found between the lowest and th...Continue Reading

References

Mar 1, 1976·Archives of Disease in Childhood·J M Tanner, R H Whitehouse
May 1, 1995·The Journal of Clinical Investigation·G S HotamisligilB M Spiegelman
Jan 1, 2003·Pediatric Research·Dan NemetDan M Cooper
Nov 6, 2003·JAMA : the Journal of the American Medical Association·Olli T RaitakariJorma S A Viikari
Nov 13, 2003·Atherosclerosis·Stefan BlankenbergLaurence Tiret
May 17, 2005·Journal of the American College of Cardiology·Christos Kasapis, Paul D Thompson
Nov 29, 2005·Best Practice & Research. Clinical Endocrinology & Metabolism·Antje KoernerWieland Kiess
May 9, 2006·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·José L MesaManuel J Castillo
Oct 10, 2006·The Journal of Hand Surgery·Jonatan R RuizAngel Gutierrez
Nov 29, 2007·International Journal of Obesity : Journal of the International Association for the Study of Obesity·F B OrtegaM Sjöström
Mar 18, 2008·The Journal of Hand Surgery·Vanesa España-RomeroJonatan R Ruiz
Jul 4, 2008·BMJ : British Medical Journal·Jonatan R RuizSteven N Blair
Jan 17, 2009·Mediators of Inflammation·Neha Mathur, Bente Klarlund Pedersen
Jun 23, 2009·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Katalin EderAndras K Fulop
Jun 10, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·D Martinez-GomezUNKNOWN AFINOS Study Group
Feb 1, 2011·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·D Martinez-GomezUNKNOWN AFINOS Study Group
Nov 16, 2011·The Journal of Pediatrics·David Jiménez-PavónUNKNOWN HELENA Study Group
Mar 23, 2012·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·Peter A HosickJoanne S Harrell
Nov 9, 2012·Medicine and Science in Sports and Exercise·Jostein Steene-JohannessenSigmund A Anderssen
Mar 19, 2013·Pediatric Exercise Science·Peter HosickJoanne Harrell
Jun 26, 2013·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Magdalena SobieskaWłodzimierz Samborski
Jul 6, 2013·Pediatric Obesity·E G ArteroUNKNOWN HELENA study group
Apr 7, 2016·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·C Agostinis-SobrinhoJ Mota
Oct 26, 2016·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·V Segura-JiménezJ Castro-Piñero
Nov 25, 2016·Scandinavian Journal of Medicine & Science in Sports·C A Agostinis-SobrinhoR Santos

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Citations

Jul 29, 2020·Journal of Clinical Medicine·Dorota Kostrzewa-NowakRobert Nowak
Jan 29, 2021·Physiology & Behavior·Tapia-Serrano Miguel AngelSánchez-Miguel Pedro Antonio
Sep 18, 2021·World Journal of Pediatrics : WJP·Tiago Rodrigues de LimaDiego Augusto Santos Silva
Jan 13, 2022·Sports Medicine·Tiago Rodrigues de LimaDiego Augusto Santos Silva

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Methods Mentioned

BETA
Assay

Software Mentioned

Statistical Package for the Social Sciences

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