Independent component analysis in spiking neurons

PLoS Computational Biology
Cristina SavinJochen Triesch


Although models based on independent component analysis (ICA) have been successful in explaining various properties of sensory coding in the cortex, it remains unclear how networks of spiking neurons using realistic plasticity rules can realize such computation. Here, we propose a biologically plausible mechanism for ICA-like learning with spiking neurons. Our model combines spike-timing dependent plasticity and synaptic scaling with an intrinsic plasticity rule that regulates neuronal excitability to maximize information transmission. We show that a stochastically spiking neuron learns one independent component for inputs encoded either as rates or using spike-spike correlations. Furthermore, different independent components can be recovered, when the activity of different neurons is decorrelated by adaptive lateral inhibition.


Jan 1, 1990·Biological cybernetics·P Földiák
Mar 1, 1990·Journal of Neurology, Neurosurgery, and Psychiatry·N Kapur
Jan 13, 1998·Vision Research·B A Olshausen, D J Field
Jan 13, 1998·Vision Research·A J Bell, T J Sejnowski
Feb 3, 1998·Proceedings. Biological Sciences·R BaddeleyE T Rolls
Apr 2, 1998·Proceedings. Biological Sciences·J H van Hateren, A van der Schaaf
Jun 20, 2001·Medical Engineering & Physics·H Liang
Jul 7, 2001·Neural Computation·A HyvärinenM Inki
Aug 25, 2001·Annual Review of Neuroscience·E P Simoncelli, B A Olshausen
Sep 21, 2001·Network : Computation in Neural Systems·H Barlow
Mar 21, 2003·Current Biology : CB·Peter Lennie
May 15, 2003·Current Opinion in Neurobiology·Eero P Simoncelli
Jun 21, 2003·Neural Computation·Eugene M Izhikevich, Niraj S Desai
Nov 5, 2003·Nature Reviews. Neuroscience·Wei Zhang, David J Linden
Jan 22, 2004·Nature Reviews. Neuroscience·Gina G Turrigiano, Sacha B Nelson
Feb 20, 2004·Journal of Neurophysiology·Robert H Cudmore, Gina G Turrigiano
Feb 21, 2004·Nature Reviews. Neuroscience·Susana Martinez-CondeDavid H Hubel
Aug 24, 2004·Current Opinion in Neurobiology·Bruno A Olshausen, David J Field
Mar 30, 2005·Proceedings of the National Academy of Sciences of the United States of America·Taro ToyoizumiWulfram Gerstner
Dec 28, 2005·Neural Computation·Michael S FalconbridgeDavid R Badcock
Sep 22, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jean-Pascal Pfister, Wulfram Gerstner
Mar 14, 2007·Neural Computation·Jochen Triesch
Jan 11, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·G Björn ChristiansonJennifer F Linden
Jan 16, 2008·Neural Computation·Cornelius Weber, Jochen Triesch
Jan 1, 1997·IEEE Transactions on Neural Networks·J KarhunenJ Joutsensalo
Feb 7, 2009·Neural Computation·Jakob H MackeMatthias Bethge
Jul 29, 2009·Neural Computation·Lucas C ParraAnthony J Bell
Jan 26, 2010·Nature Neuroscience·Claudia ClopathWulfram Gerstner
Apr 28, 2010·PLoS Computational Biology·Cristina SavinJochen Triesch

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