Independent origins of subgroup Bl + B2 and subgroup B3 metallo-beta-lactamases

Journal of Molecular Evolution
Barry G HallMiriam Barlow

Abstract

The metallo-beta-lactamases constitute Class B in the Ambler classification of beta-lactamases and are divided into three subclasses: Bl, B2, and B3. Bayesian phylogenies of the Subclass B1 + B2 and Subclass B3 metallo-beta-lactamases and their homologs show that the beta-lactam-hydrolyzing function evolved independently within each group. In Subclass B1+B2 that function evolved about 1 billion years ago, and in Subclass B3 it evolved before the divergence of the Gram-positive and Gram-negative eubacteria, about 2 billion years ago. These results lend additional support to the proposal that the metallo-beta-lactamases should be divided into two distinct classes.

Citations

May 2, 2012·Antimicrobial Agents and Chemotherapy·Michael WidmannPeter Oelschlaeger
Apr 30, 2008·Antimicrobial Agents and Chemotherapy·Magdalena StoczkoJean-Denis Docquier
Jun 26, 2007·Applied and Environmental Microbiology·Wei-Jen ChenMarie-France Corio-Costet
Jun 4, 2008·Folia Histochemica Et Cytobiologica·Paweł SachaElzbieta Tryniszewska
Sep 9, 2010·Annual Review of Genetics·Mariya Morar, Gerard D Wright
Jan 1, 2013·Intrinsically Disordered Proteins·Sandeep ChakrabortyBjarni Asgeirsson
Apr 4, 2014·Metallomics : Integrated Biometal Science·A I KarsisiotisG C K Roberts
Apr 29, 2014·Journal of Molecular Biology·Florian Baier, Nobuhiko Tokuriki
Dec 6, 2018·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Stéphanie Le PageDidier Raoult
Oct 4, 2008·Pest Management Science·Stefano Ff TorrianiHelge Sierotzki
Oct 10, 2008·The ISME Journal·Heather K AllenJo Handelsman
Jan 4, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Brad SpellbergUNKNOWN Infectious Diseases Society of America
Apr 11, 2015·Evolutionary Applications·Qiuzhi ChangWilliam P Hanage
Jun 28, 2005·Antimicrobial Agents and Chemotherapy·Gianpiero GarauBarry G Hall
Oct 22, 2016·Annals of the New York Academy of Sciences·Boahemaa Adu-OppongGautam Dantas
Oct 3, 2020·The Journal of Antimicrobial Chemotherapy·Fanny BerglundErik Kristiansson
Jun 29, 2017·Annual Review of Microbiology·Matthew D Surette, Gerard D Wright
Sep 19, 2020·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Lili WangHao Zhang
Apr 21, 2018·Frontiers in Microbiology·Erica L FonsecaAna C P Vicente
Oct 18, 2020·Antibiotics·Shashi B KumarOuliana Ziouzenkova
Mar 19, 2021·EcoSal Plus·Nicholas WaglechnerGerard D Wright
Jul 8, 2008·Journal of Inorganic Biochemistry·Peter Oelschlaeger
Jul 27, 2021·Antimicrobial Agents and Chemotherapy·Liam A WilsonGerhard Schenk

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