PMID: 11320456Apr 26, 2001Paper

Independent risk for cardiovascular disease predicted by modified continuous score electrocardiographic criteria for 6-year incidence and regression of left ventricular hypertrophy among clinically disease free men: 16-year follow-up for the multiple risk factor intervention trial

Journal of Electrocardiology
R J PrineasMRFIT Research Group

Abstract

Risk prediction for electrocardiographic (ECG) left ventricular hypertrophy related criteria, used in clinical trials, and epidemiologic studies of clinically healthy people, has depended in the past on dichotomous classification of ECG LVH criteria. Recent analyses have shown that more sensitive methods of LVH ECG classification without loss of specificity are needed to improve on dichotomous classification. This was done by relating six year incident significant change in continuous score criteria of ECG LVH to the 16 year (10 year post trial) coronary heart disease (CHD) and cardiovascular disease (CVD) mortality among 12,866 men, free of clinical disease, aged 35 to 57 years at baseline in the Multiple Risk Factor Intervention Trial. It was found that significant change in continuous ECG LVH criteria was a stronger independent predictor of future CHD and CVD mortality than was use of dichotomous classification of the same criteria. It was also demonstrated that increase in continuous ECG LVH indexes, below previous dichotomous thresholds independently (of standard CVD risk factors, including increase in obesity-indicated by an increase in adult BMI) predicted excess CHD and CVD mortality and that combinations of continuous ...Continue Reading

Citations

Sep 24, 2016·Journal of Hypertension·Maria L MuiesanUNKNOWN Moli-sani Study Investigators
May 23, 2002·American Journal of Respiratory and Critical Care Medicine·Raouf S AminSteven R Daniels
Jun 19, 2009·Anesthesia and Analgesia·Deborah A SchwengelEugenie S Heitmiller
Nov 21, 2017·Journal of the American Heart Association·Peter M OkinRichard B Devereux
Nov 15, 2019·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Evangelos OikonomouDimitris Tousoulis
Oct 13, 2007·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Walid HassanMohamed Shoukri
Nov 26, 2010·Circulation·Philip GreenlandUNKNOWN American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
May 19, 2006·Journal of Human Hypertension·R L AntikainenUNKNOWN Department of Health and Social Security Hypertension Care Computer Project (DHCCP)
Feb 23, 2021·Frontiers in Physiology·Mira Anette E HaukilahtiHeikki V Huikuri

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