Indeterminate Adnexal Cysts at US: Prevalence and Characteristics of Ovarian Cancer

Radiology
Elizabeth A SadowskiKatherine E Maturen

Abstract

Purpose To assess the prevalence of indeterminate adnexal cysts in women presenting to academic medical centers for pelvic ultrasonography (US), determine the incidence of malignancy, and identify cyst and patient characteristics that are predictive of malignancy. Materials and Methods A multicenter study of US-detected adnexal cysts with appropriate follow-up (surgical pathologic examination, imaging and/or clinical examination) was conducted from January 2008 to June 2012. Indeterminate cysts were classified as category 1 (typical benign appearing cysts >5 cm) or category 2 (cysts with avascular solid components) on the basis of a combination of definitions in the existing literature. The incidence of neoplasms and malignant tumors was calculated. Patient and cyst characteristics associated with neoplasm and malignant tumors were evaluated with the χ2 test or Fisher exact test for categorical variables and the t test for continuous variables. A backward stepwise logistic regression model was performed for two outcomes: (a) the presence of any neoplasm (benign or malignant) and (b) the presence of a malignant tumor. Results There were 1637 women with an adnexal cyst at US; 391 (mean age = 41.8 years ± 13.5.1; range = 17-91 yea...Continue Reading

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Citations

Sep 5, 2020·The British Journal of Radiology·Anuradha ChandramohanBetty Simon
Jul 28, 2020·Journal of Magnetic Resonance Imaging : JMRI·Mohammad Abd Alkhalik BashaTaghreed M Azmy
Oct 21, 2020·Abdominal Radiology·Erica B SteinKatherine E Maturen
Jan 24, 2021·Journal of the American College of Radiology : JACR·Caroline ReinholdIsabelle Thomassin-Naggara
May 1, 2021·The British Journal of Radiology·Elizabeth A SadowskiIsabelle Thomassin-Naggara
May 8, 2021·European Journal of Radiology·Yu-Ting ShenHui-Xiong Xu
Aug 22, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Isabelle Thomassin-NaggaraCaroline Reinhold
Oct 2, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Sanjay RaoSree Harsha Tirumani

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