Indication and Usefulness of Bile Juice Cytology for Diagnosis of Gallbladder Cancer

Gastroenterology Research and Practice
Hiroshi ItsukiKazuaki Chayama

Abstract

We examined the effectiveness of bile juice cytology for distinguishing between benign and malignant gallbladder lesions of the protruding type with various sampling points, sampling methods, and macroscopic forms in order to discuss the effectiveness of the endoscopic transpapillary gallbladder drainage (ETGD) cytology. We studied 162 cases of patients with a lesion localized within the gallbladder. At first, we examined the effectiveness for diagnosis of ETBD cytology using ERC and then that of the first ETGD cytology after placing the ETGD. Next, we examined the diagnostic effectiveness of the washed ETGD cytology by using the ETGD. Finally, we examined complications. In the final diagnoses, we identified 33 cases of adenocarcinoma, 10 cases of adenoma, 63 cases of ADM, 35 cases of nonneoplastic polyp, and 21 cases of chronic cholecystitis. It was found that the sensitivity of ETBD cytology was 3.6% and that of ETGD cytology was 59.1%. In the comparison of diagnostic effectiveness of cytologic diagnosis using samples of bile juice from the gallbladder collected by different methods, the sensitivities were 38.9% and 73.3% for the first and washed ETGD cytologies, respectively. In the comparison of the diagnostic effectiveness...Continue Reading

References

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Citations

Apr 24, 2020·Expert Review of Gastroenterology & Hepatology·Pankaj GuptaManavjit Singh Sandhu
Jan 29, 2021·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Kiyoyuki KobayashiTsutomu Masaki
Jan 29, 2020·Euroasian Journal of Hepato-gastroenterology·Osman Nuri DilekFatma Hüsniye Dilek
May 28, 2019·Case Reports in Gastroenterology·Naotake Funamizu, Yukio Nakabayashi

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