Indications and results of endovascular therapy of critical limb ischemia

Der Radiologe
A ZimmermannH-H Eckstein

Abstract

Critical limb ischemia (CLI) is the most severe form of peripheral artery occlusive disease and is characterized by high amputation, morbidity and mortality rates. Therefore, revascularization is the essential step in therapy for retention of the affected limb. Although for a long time bypass surgery represented the gold standard in the treatment of CLI, in recent years there has been a disproportionate increase of endovascular treatment despite the lack of level-data. In this review the indications and results of endovascular therapy of CLI are presented on the basis of published data. A literature search was carried out to identify publications that compared the results of endovascular and surgical therapy as well as observational studies about different endovascular techniques. The BASIL study provided the highest quality data comparing endovascular and surgical treatment of CLI. The long-term data of the BASIL trial showed that apart from patients with a suitable vein and a life expectancy of more than 2 years, first line endovascular therapy is equivalent to surgical treatment. The equivalence could also be demonstrated in a meta-analysis comparing operative and endovascular treatment of CLI. The CLI is a disease with high...Continue Reading

References

Jan 1, 1976·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·A Grüntzig
Jul 6, 2004·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·E S van der ZaagM J Jacobs
Jan 16, 2007·Journal of Vascular Surgery·L NorgrenUNKNOWN TASC II Working Group
Mar 29, 2008·Journal of Vascular Surgery·Marcello RomitiNelson De Luccia
Apr 22, 2008·The Cochrane Database of Systematic Reviews·F Fowkes, G C Leng
May 15, 2010·Journal of Vascular Surgery·Andrew W Bradbury, UNKNOWN BASIL trial Investigators and Participants
Feb 22, 2011·Journal of Vascular Surgery·Philip P GoodneyUNKNOWN Vascular Study Group of New England
Sep 3, 2011·Journal of the American College of Cardiology·Andrej SchmidtDierk Scheinert
Nov 7, 2012·VASA. Zeitschrift für Gefässkrankheiten·A ZimmermannH-H Eckstein
Sep 23, 2014·Techniques in Vascular and Interventional Radiology·Alik FarberMatthew Menard

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