PMID: 16614620Apr 15, 2006Paper

Indications for intravenous immunoglobulins

La Presse médicale
L Mouthon

Abstract

Intravenous immunoglobulins (IgIV) are therapeutic preparations of polyclonal human IgG, obtained from a pool of plasma from more than 1000 healthy donors. This article discusses only some of the recognized indications (Group I) and some of those currently under evaluation (Group II) for the treatment of autoimmune and systemic inflammatory diseases. Perspectives for IgIV use are approached through three diseases, each providing a different model of immune system modulation: ocular cicatricial pemphigoid, where an autoimmune reaction is modulated; alloimmunization of chronic hemodialysis patients, where alloreactivity can be modulated; and streptococcal toxic shock, where anti-infectious immunity may be modulated.

Citations

Nov 4, 2009·Clinical and Experimental Immunology·H-P HartungS Jolles
May 21, 2011·Expert Review of Clinical Immunology·Nima RezaeiHans D Ochs
May 15, 2007·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Loïc Guillevin, Christian Pagnoux

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