Indigenous drugs in ischemic heart disease in patients with diabetes

The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy
Shridhar Dwivedi, Amitesh Aggarwal

Abstract

India is currently facing the silent epidemic of ischemic heart disease, type 2 diabetes mellitus (T2DM), hypertension, and stroke. Both diabetes and ischemic heart disease appear in Indian people a decade earlier compared to whites. The recent evidence that certain medicinal plants possess hypoglycemic, lipid-lowering, and immunomodulating properties on account of their rich flavonoid and/or other glucose-lowering active constituents merits scientific scrutiny in this regard. The present communication aims to give a brief review of those plants that could be useful in T2DM associated with hypertension, ischemic heart disease, and/or dyslipidemia. Aegle marmelos (bael), Allium sativum (garlic), Curcuma domestica (turmeric), Eugenia jambolana (jamun), Murraya koenigii (curry leaves), Trigonella foenum graecum (fenugreek), and Terminalia arjuna (arjun) have been found to be useful in diabetes associated with ischemic heart disease. Their active biomolecules have been identified. They have also been demonstrated to be safe in long-term use. Further clinical research regarding their potency and efficacy vis-à-vis oral hypoglycemics needs to done.

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Citations

Nov 1, 2012·BMC Complementary and Alternative Medicine·Nasser M Al-DaghriSoundararajan Krishnaswamy
Jun 21, 2016·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Bhavesh C VariyaSnehal S Patel
Mar 31, 2018·International Journal of Molecular Sciences·Attila CzompaIstvan Lekli

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