Individual differences in learning correlate with modulation of brain activity induced by transcranial direct current stimulation

PloS One
Brian FalconeDaniel E Callan

Abstract

Transcranial direct current stimulation (tDCS) has been shown to enhance cognitive performance on a variety of tasks. It is hypothesized that tDCS enhances performance by affecting task related cortical excitability changes in networks underlying or connected to the site of stimulation facilitating long term potentiation. However, many recent studies have called into question the reliability and efficacy of tDCS to induce modulatory changes in brain activity. In this study, our goal is to investigate the individual differences in tDCS induced modulatory effects on brain activity related to the degree of enhancement in performance, providing insight into this lack of reliability. In accomplishing this goal, we used functional magnetic resonance imaging (fMRI) concurrently with tDCS stimulation (1 mA, 30 minutes duration) using a visual search task simulating real world conditions. The experiment consisted of three fMRI sessions: pre-training (no performance feedback), training (performance feedback which included response accuracy and target location and either real tDCS or sham stimulation given), and post-training (no performance feedback). The right posterior parietal cortex was selected as the site of anodal tDCS based on it...Continue Reading

References

Sep 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·A B Falcone
Jun 1, 1996·Computers and Biomedical Research, an International Journal·R W Cox
Mar 14, 1998·Proceedings of the National Academy of Sciences of the United States of America·M Corbetta
Dec 3, 1998·Experimental Brain Research·S ClarkeA Cowey
Jan 29, 2000·The European Journal of Neuroscience·A Bartels, S Zeki
Feb 17, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J BaudewigJ Frahm
May 8, 2002·Nature Reviews. Neuroscience·Maurizio Corbetta, Gordon L Shulman
Dec 18, 2003·Supplements to Clinical Neurophysiology·Michael A NitscheWalter Paulus
Dec 24, 2003·Radiation Protection Dosimetry·J G R JefferysJ Fox
Feb 24, 2004·The Journal of Physiology·Marom BiksonJohn G R Jefferys
Sep 8, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M A NitscheB-U Meyer
Apr 24, 2007·Vision Research·Serge O Dumoulin, Robert F Hess
Jan 4, 2008·Journal of Neurophysiology·Joakim Vinberg, Kalanit Grill-Spector
Jan 22, 2008·Neuropsychologia·John L Barbur, Karoline Spang
May 10, 2008·Neuron·Maurizio CorbettaGordon L Shulman
Oct 1, 2009·The European Journal of Neuroscience·C J StaggH Johansen-Berg
Feb 20, 2010·PLoS Computational Biology·Takashi NakanoKenji Doya
May 4, 2010·NeuroImage·Damien J MannionColin W G Clifford
Mar 19, 2011·Brain : a Journal of Neurology·Christian Grefkes, Gereon R Fink
Aug 9, 2011·Current Biology : CB·Rachel HollandJennifer Crinion
Oct 13, 2011·Experimental Brain Research·Liron JacobsonMichal Lavidor
Oct 28, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Daniel KeeserFrank Padberg
Feb 4, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Marcus MeinzerAgnes Flöel
Apr 6, 2012·Restorative Neurology and Neuroscience·Andrea AntalMark W Greenlee
Aug 3, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Philip TsengChi-Hung Juan

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Citations

Feb 25, 2021·Cyberpsychology, Behavior and Social Networking·Justin Asbee, Thomas D Parsons
May 11, 2021·Frontiers in Pharmacology·Andrés Molero-ChamizoJosé R Alameda Bailén

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Methods Mentioned

BETA
infrared spectroscopy
feature extraction

Software Mentioned

SPM Anatomy Toolbox
3dClustSim
3dFWHMx AFNI
Talairach Client
AFNI
Virtual Battlespace 2 ( VBS2 )
WFU PickAtlas Tool
SPM8

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