Individual differences in predicting aversive events and modulating contextual anxiety in a context and cue conditioning paradigm

Biological Psychology
Johanna M P Baas

Abstract

Deficient fear conditioning leads to maladaptive contextual anxiety as predicting danger is a key factor in regulating anxiety. A virtual reality conditioning task was used to evaluate cue learning and contextual anxiety with fear-potentiated startle and subjective fear in two experiments. In Experiment 1, failure to condition to a cue resulted in a constant state of context anxiety (subjective fearfulness and startle). Trait anxiety was unrelated to learning cue contingencies but the participants who failed to learn scored lower on a self-report measure of attentional control. Part of the group that learned the cue contingency failed to deduce safety of the context and hence did not reduce their contextual anxiety. Experiment 2 specifically focused on isolating this process and demonstrated an inverse association between trait anxiety and adaptive modulation of contextual anxiety. In conclusion, predicting threat aids in but not automatically implies successful regulation of contextual anxiety. High trait anxiety may increase risk of deficient modulation of contextual anxiety.

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Citations

Feb 7, 2013·Biological Psychology·Evelyn Glotzbach-SchoonAndreas Mühlberger
Sep 27, 2012·Translational Psychiatry·I HeitlandJ M P Baas
Sep 25, 2015·Psychophysiology·Christopher T SegePeter J Lang
Sep 18, 2015·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Jennifer A SumnerKarestan C Koenen
Dec 3, 2014·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Johanna M P Baas, Ivo Heitland
Oct 5, 2013·Journal of Psychiatric Research·Marit SijbrandijJohanna M P Baas
Dec 4, 2013·Cognition & Emotion·Miquel Tortella-FeliuAntonia P Pacheco-Unguetti
May 20, 2015·Neurobiology of Learning and Memory·Kathrin Cohen KadoshJennifer Y F Lau
Nov 8, 2018·Journal of Neuroscience Research·Marta AndreattaPaul Pauli
Sep 27, 2018·Cognitive, Affective & Behavioral Neuroscience·Gyongyi KokonyeiGabriella Juhasz
Sep 16, 2021·Journal of Applied Behavior Analysis·Adithyan RajaramanGregory P Hanley

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