Individual hemoglobin mass response to normobaric and hypobaric "live high-train low": A one-year crossover study

Journal of Applied Physiology
Anna HauserJ P Wehrlin

Abstract

The purpose of this research was to compare individual hemoglobin mass (Hbmass) changes following a live high-train low (LHTL) altitude training camp under either normobaric hypoxia (NH) or hypobaric hypoxia (HH) conditions in endurance athletes. In a crossover design with a one-year washout, 15 male triathletes randomly performed two 18-day LHTL training camps in either HH or NH. All athletes slept at 2,250 meters and trained at altitudes <1,200 meters. Hbmass was measured in duplicate with the optimized carbon monoxide rebreathing method before (pre) and immediately after (post) each 18-day training camp. Hbmass increased similarly in HH (916-957 g, 4.5 ± 2.2%, P < 0.001) and in NH (918-953 g, 3.8 ± 2.6%, P < 0.001). Hbmass changes did not differ between HH and NH (P = 0.42). There was substantial interindividual variability among subjects to both interventions (i.e., individual responsiveness or the individual variation in the response to an intervention free of technical noise): 0.9% in HH and 1.7% in NH. However, a correlation between intraindividual ΔHbmass changes (%) in HH and in NH (r = 0.52, P = 0.048) was observed. HH and NH evoked similar mean Hbmass increases following LHTL. Among the mean Hbmass changes, there was...Continue Reading

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Feb 15, 2018·Nutrients·Raúl DomínguezAlberto Pérez-López
Sep 29, 2017·European Journal of Applied Physiology·Nicolas BourdillonGrégoire P Millet
Mar 15, 2018·Medicine and Science in Sports and Exercise·Laura A Garvican-LewisChristopher J Gore
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Jun 6, 2018·Frontiers in Physiology·Martin BurtscherHeimo Mairbäurl
Aug 8, 2020·High Altitude Medicine & Biology·Reinhard PuehringerMartin Burtscher
Aug 13, 2020·Scandinavian Journal of Medicine & Science in Sports·Ari NummelaJuha E Peltonen
Jan 12, 2021·European Journal of Applied Physiology·Bing YanOlivier Girard
Apr 2, 2021·Frontiers in Sports and Active Living·Jon Peter Wehrlin, Thomas Steiner
Apr 6, 2021·Frontiers in Sports and Active Living·Tiffany AstolfiRaphael Faiss

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