Individual pain sensitivity is associated with resting-state cortical activities in healthy individuals but not in patients with migraine: a magnetoencephalography study

The Journal of Headache and Pain
Fu-Jung HsiaoShuu-Jiun Wang

Abstract

Pain sensitivity may determine the risk, severity, prognosis, and efficacy of treatment of clinical pain. Magnetic resonance imaging studies have linked thermal pain sensitivity to changes in brain structure. However, the neural correlates of mechanical pain sensitivity remain to be clarified through investigation of direct neural activities on the resting-state cortical oscillation and synchrony. We recorded the resting-state magnetoencephalographic (MEG) activities of 27 healthy individuals and 30 patients with episodic migraine (EM) and analyzed the source-based oscillatory powers and functional connectivity at 2 to 59 Hz in pain-related cortical regions, which are the bilateral anterior cingulate cortex (ACC), medial orbitofrontal (MOF) cortex, lateral orbitofrontal (LOF) cortex, insula cortex, primary somatosensory cortex (SI), primary motor cortex (MI), and posterior cingulate cortex (PCC). The mechanical punctate pain threshold (MPPT) was obtained at the supraorbital area (the first branch of the trigeminal nerve dermatome, V1) and the forearm (the first thoracic nerve dermatome, T1) and further correlated with MEG measures. The MPPT is inversely correlated with the resting-state relative powers of gamma oscillation in h...Continue Reading

References

Apr 8, 1998·Journal of Computer Assisted Tomography·C J HolmesA C Evans
Mar 10, 1999·Physics in Medicine and Biology·M X HuangR M Leahy
Oct 9, 1999·Journal of Neurophysiology·R C CoghillM J Iadarola
Jan 15, 2000·Journal of the American College of Cardiology·S E SheiferT A Manolio
Apr 12, 2003·Brain : a Journal of Neurology·J LorenzK L Casey
Jun 26, 2003·Proceedings of the National Academy of Sciences of the United States of America·Robert C CoghillYi-Fen Yen
Sep 24, 2004·Brain Topography·Samu TauluJuha Simola
Apr 2, 2005·Nature Reviews. Neuroscience·Alfons Schnitzler, Joachim Gross
Jun 28, 2005·European Journal of Pain : EJP·A Vania ApkarianJon-Kar Zubieta
Feb 9, 2006·Brain Research Bulletin·Claudio BabiloniPaolo M Rossini
Apr 26, 2007·PLoS Biology·Joachim GrossMarkus Ploner
Aug 31, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael HauckAndreas K Engel
Oct 13, 2007·Brain : a Journal of Neurology·Timothy A NorburyStephen B McMahon
Feb 3, 2009·The Journal of Pain : Official Journal of the American Pain Society·Christopher S NielsenDonald D Price
Feb 25, 2009·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Fu-Jung HsiaoYung-Yang Lin
Dec 2, 2009·Proceedings of the National Academy of Sciences of the United States of America·Markus PlonerIrene Tracey
May 18, 2011·Computational Intelligence and Neuroscience·François TadelRichard M Leahy
Apr 21, 2012·Pain·Nathalie ErpeldingKaren D Davis
Jun 1, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Z G ZhangG D Iannetti
Dec 12, 2012·Frontiers in Neuroscience·Arno Klein, Jason Tourville
Jan 16, 2013·Proceedings of the National Academy of Sciences of the United States of America·Sheraz KhanTal Kenet
Sep 12, 2013·Pain·Luis Garcia-Larrea, Roland Peyron
Jan 18, 2014·Nature Reviews. Neuroscience·Thomas Akam, Dimitri M Kullmann
Apr 23, 2014·Trends in Cognitive Sciences·Daniel SenkowskiAndreas K Engel
May 13, 2014·Annals of Neurology·Flavia ManciniGian Domenico Iannetti
May 15, 2015·The Journal of Headache and Pain·Hongxing LiuXiaoshan Wang
May 6, 2016·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Philipp Taesler, Michael Rose
Jun 6, 2016·NeuroImage·G L ColcloughS M Smith
Jul 16, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Feng LiJingping Shi
May 26, 2017·Cephalalgia : an International Journal of Headache·Fu-Jung HsiaoWei-Ta Chen
Aug 23, 2017·Proceedings of the National Academy of Sciences of the United States of America·Wei TangSteven M Stufflebeam

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Software Mentioned

MaxFilter
BrainVISA
Mindboggle
Neuromag
Elekta Neuromag
Brainstorm
EM

Related Concepts

Related Feeds

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.