Individualized gating windows based on four-dimensional CT information for respiration-gated radiotherapy

Physics in Medicine and Biology
Nicole M WinkLei Xing

Abstract

The purpose of this work is to relate the gating window and displacement of a moving tumor target and develop a systematic method to individualize the gating window for respiration-gated radiation therapy (RT). As the relationship between patient anatomy and respiration phase is contained in 4D images, we aim to quantify this information and utilize the data to guide gated treatment planning. After 4D image acquisition, the target and organs at risk were delineated manually on the selected gating phase. The contours were propagated automatically onto every phase-specific image set using a control volume-based contour mapping technique. The mean and maximum distances between the contours in the gating phase and each of other phases were evaluated in three dimensions. The gating window was determined in such a way that the residual movement of the target within the window is smaller or equal to the patient's setup error. The proposed method was applied to plan the gated treatments of 12 lung cancer patients. As a result of this work, a method to calculate patient-specific gating windows has been developed. The general reference drawn from this study is that, with the aide of 4D images and automated 4D contour propagation, it is f...Continue Reading

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Citations

Nov 29, 2011·Australasian Physical & Engineering Sciences in Medicine·L DunnR D Franich
Oct 5, 2013·Medical Physics·Eric W PepinHiroki Shirato
Sep 27, 2014·Radiation Oncology·Benjamin FahimianLei Xing
Jul 31, 2012·Seminars in Nuclear Medicine·Valentino BettinardiMaria Carla Gilardi
Mar 22, 2014·Physics in Medicine and Biology·Hanlin WanParag Parikh
Mar 27, 2018·Journal of Applied Clinical Medical Physics·Evan Silverstein, Michael Snyder

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