Individually-tailored treatment of chronic obstructive pulmonary disease: a proposed change

Archivos de bronconeumología
M Miravitlles

Abstract

Chronic obstructive pulmonary disease (COPD) is a highly prevalent but poorly defined disease and there is wide confusion regarding its treatment. The available knowledge should allow guidelines for specific treatment to be established according to each patient's clinical features. The present article describes a proposal for individually-tailored treatment. Long-acting bronchodilators, alone or in various combinations, would be the basis of treatment and inhaled corticosteroids (IC) should be used in a subgroup with well-defined characteristics. The latest studies indicate that the benefits of IC are limited in COPD and that the risks are not inconsiderable. Consequently, these drugs should be limited to "responders" and should always be administered in association with a long-acting beta(2) bronchodilator. The pathogenesis of this disease should be studied in greater depth and patients should be classified according to their severity, the frequency of acute exacerbations, their reversibility, comorbidity and concomitant medication in order to choose the most appropriate treatment.

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Citations

Sep 11, 2012·Multidisciplinary Respiratory Medicine·Barbara Piras, Marc Miravitlles
Feb 22, 2012·Archivos de bronconeumología·Juan José Soler-CataluñaJosé Luis Viejo
Dec 27, 2011·Archivos de bronconeumología·Marc MiravitllesJuan José Soler-Cataluña
Jun 24, 2011·Revista clínica española·J C Martín Escudero
Jul 16, 2011·Archivos de bronconeumología·UNKNOWN Grupo de Trabajo de GESEPOC
Feb 22, 2011·Archivos de bronconeumología·Julio AncocheaJavier de Miguel Díez
Jun 19, 2012·Atencion primaria·Marc MiravitllesJulio Ancochea
Mar 29, 2011·Archivos de bronconeumología·Marc Miravitlles

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