Indocyanine green fluorescence-navigated thoracoscopic anatomical segmentectomy

Journal of Visualized Surgery
Mingyon MunKen Nakagawa

Abstract

To evaluate the feasibility and efficacy of thoracoscopic anatomical segmentectomy (TS-S) using three-dimensional computed tomography (3D-CT) reconstruction and indocyanine green-fluorescence (ICGF) navigation. Twenty TS-S procedures were performed for 15 primary lung cancers and 5 metastatic lung tumors. Preoperatively we evaluated the target segmental pulmonary artery and created a virtual intersegmental plane using 3D-CT reconstruction. Intraoperatively, the target segmental artery and bronchus were divided, and after intravenous systemic injection of indocyanine green (ICG, 0.25 mg/kg), ICGF of the non-target segments (NTS) was observed using infrared thoracoscopy (KARL STORZ Endoskope Japan K.K., Tokyo, Japan). We marked the border between target and NTS with electrocautery and divided the lung parenchyma along this border using electrocautery or staples. Strength of contrast between target and NTS was quantified as contrast index (CI) and compared over time. ICGF provided demarcation of sufficient clarity and duration to mark the lung surface in 19 patients (95%). TS-S was successfully performed in all patients. Mean operative duration was 186 min (90-310 min) and mean blood loss was 30 mL (0-107 mL). Demarcation appeared...Continue Reading

Citations

May 12, 2018·Journal of the Royal Society of Medicine·David Waller
Nov 28, 2019·Interactive Cardiovascular and Thoracic Surgery·Marco AndolfiDominique Gossot
Dec 7, 2020·The Journal of Surgical Research·Takuya MatsuiHiroaki Kuroda
Feb 19, 2019·The Journal of Thoracic and Cardiovascular Surgery·Moishe Liberman
May 28, 2021·International Journal of Surgery Case Reports·Takaki AkamineYasunori Shikada
Jul 29, 2021·JTCVS Techniques·Masaya YotsukuraShun-Ichi Watanabe

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