PMID: 6985156Dec 30, 1982Paper

Indoleaminergic innervation of rat choroid plexus: a fluorescence histochemical study

Neuroscience Letters
P NapoleoneF Amenta

Abstract

Using a fluorescence histochemical technique we found that the precursor of serotonin, 5-hydroxytryptophan (5-HTP), is taken up by a population of nerve fiber-like structures, indoleaminergic in nature since selectively destroyed by the neurotoxin 6-hydroxytryptamine, within rat choroid plexus. Nerve fiber-like structures are localized within the wall of choroid blood vessels. More infrequently nerve fibers end in the stroma or in close relation to epithelial cells of the plexus. The electrolytic lesioning of raphe nuclei causes the disappearance of 5-HTP fluorescence, suggesting that these nerve fibers originate from raphe nuclei. These results suggest a direct influence of indoleaminergic pathways originating from the brainstem on the blood flow through choroid plexus as well as on the production of cerebrospinal fluid.

References

Jun 29, 1979·Brain Research·M A MoskowitzA Schlosberg
Nov 1, 1970·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·A Björklund, U Stenevi
Jan 1, 1980·Annual Review of Neuroscience·G Jonsson
Feb 21, 1980·The New England Journal of Medicine·V S Caviness, P O'Brien
Jul 1, 1980·The Practitioner·P A Millac

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Citations

Jan 1, 1987·Psychopharmacology·P J Conn, E Sanders-Bush
Jun 7, 1985·European Journal of Pharmacology·F AmentaP Geppetti
Jan 1, 1990·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·S Péraldi-RouxJ Gabrion
Oct 1, 1990·Schizophrenia Research·R SandykA E Merriam
Jun 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·P J ConnP R Hartig
May 23, 2012·Pharmacological Reviews·Van A Doze, Dianne M Perez
Mar 8, 2005·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Esa-Pekka PälvimäkiJarmo Hietala
Apr 16, 2015·Frontiers in Neuroscience·Weerapong PrasongcheanPatrizia Ferretti
May 1, 1991·The International Journal of Neuroscience·S R KayA E Merriam
Jul 1, 1993·The International Journal of Neuroscience·R Sandyk
Jul 1, 1993·The International Journal of Neuroscience·R Sandyk, G I Awerbuch
Jun 1, 1985·Cephalalgia : an International Journal of Headache·E T MacKenzieB Scatton
Oct 28, 2019·JCI Insight·Caio Henrique MazucantiJosephine M Egan
May 1, 1985·Cephalalgia : an International Journal of Headache·G Burnstock

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