Induced beta-carotene synthesis driven by triacylglycerol deposition in the unicellular alga dunaliella bardawil

Plant Physiology
S RabbaniH Kleinig

Abstract

Under stress conditions such as high light intensity or nutrient starvation, cells of the unicellular alga Dunaliella bardawil overproduce beta-carotene, which is accumulated in the plastids in newly formed triacylglycerol droplets. We report here that the formation of these sequestering structures and beta-carotene are interdependent. When the synthesis of triacylglycerol is blocked, the overproduction of beta-carotene is also inhibited. During overproduction of beta-carotene no up-regulation of phytoene synthase or phytoene desaturase is observed on the transcriptional or translational level, whereas at the same time acetyl-CoA carboxylase, the key regulatory enzyme of acyl lipid biosynthesis, is increased, at least in its enzymatic activity. We conclude that under normal conditions the carotenogenic pathway is not maximally active and may be appreciably stimulated in the presence of sequestering structures, creating a plastid-localized sink for the end product of the carotenoid biosynthetic pathway.

References

Jan 4, 1988·European Journal of Biochemistry·U MettalH Kleinig
Feb 1, 1973·Analytical Biochemistry·G R Schacterle, R L Pollack
Dec 23, 1971·Journal of Chromatography·H Kleinig, U Lempert
Oct 15, 1981·Archives of Biochemistry and Biophysics·B J NikolauC R Slack
Apr 15, 1983·The Biochemical Journal·E Turnham, D H Northcote
Jan 20, 1994·Biochimica Et Biophysica Acta·R A PageJ L Harwood
Jan 1, 1995·International Review of Cytology·B CamaraR Monéger
Jun 1, 1995·Plant Physiology·Y. SasakiY. Nagano
Jul 1, 1963·The Biochemical Journal·W G Duncombe

❮ Previous
Next ❯

Citations

Mar 17, 2010·Journal of Industrial Microbiology & Biotechnology·Lili MiaoYing Li
Jun 21, 2006·Biotechnology Letters·Leticia Sánchez-EstudilloJosé Alberto Narváez-Zapata
Aug 14, 2010·Photosynthesis Research·Yves Lemoine, Benoît Schoefs
Jul 16, 2013·Archives of Biochemistry and Biophysics·Li Li, Hui Yuan
Mar 25, 2004·Trends in Biotechnology·M Amin Hejazi, Rene H Wijffels
Mar 29, 2005·Nature Biotechnology·Jacqueline A PaineRachel Drake
Jul 14, 2012·Journal of Experimental Botany·Bianyun YuAbdelali Hannoufa
Jul 10, 2007·Transgenic Research·Li Li, Joyce Van Eck
May 15, 2008·The Plant Journal : for Cell and Molecular Biology·Qiang HuAl Darzins
Apr 30, 2015·Photosynthesis Research·João C VarelaRosa León
Feb 18, 2016·Biochimica Et Biophysica Acta·Krzysztof ZienkiewiczChristoph Benning
Jun 12, 2014·Briefings in Functional Genomics·Manoj K DharSanjana Kaul
Jan 13, 2015·Applied Biochemistry and Biotechnology·Ramachandran SrinivasanKodiveri Muthukalianan Gothandam
Sep 26, 2014·Journal of Agricultural and Food Chemistry·Jaslyn Jie Lin LeeWei-Ning Chen
May 20, 2015·Biotechnology Advances·Milada VitovaVilem Zachleder
Feb 13, 2017·Ecotoxicology and Environmental Safety·Eric M TorresJason C Quinn
Jul 7, 2011·Marine Drugs·Ana Catarina GuedesFrancisco Xavier Malcata
Oct 11, 2017·Journal of Zhejiang University. Science. B·Ling HongPhilip C Miller
Jul 29, 2018·The Journal of Eukaryotic Microbiology·Pattarasiri Rangsrikitphoti, Dion G Durnford
Oct 8, 2004·Biotechnology and Bioengineering·M A HejaziR H Wijffels
Feb 2, 2019·Critical Reviews in Food Science and Nutrition·Dinesh Kumar SainiPratyoosh Shukla
Feb 28, 2009·Journal of Applied Microbiology·A Hosseini Tafreshi, M Shariati
Mar 17, 2010·Biotechnology and Bioengineering·Packo P LamersRené H Wijffels
Oct 5, 2010·Journal of Integrative Plant Biology·Tian-Hu SunShan Lu

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.