PMID: 9428895Jan 16, 1998Paper

Induced hypervolemia and inotropic support for acute cerebral arterial insufficiency: an underused therapy

Surgical Neurology
B J DukeG W Kindt

Abstract

Hypervolemia and induced systemic hypertension are generally considered the standard approach to the treatment of vasospasm. Despite evidence in favor of its efficacy, this therapy is used rarely in acute cerebrovascular occlusion. We present a case supporting this treatment paradigm. A patient developed aphasia and hemiplegia 8 h after carotid endarterectomy caused by embolic occlusion of the middle cerebral artery. Hyperdynamic/hypervolemic therapy was instituted. Serial angiograms filmed over the next 8 h demonstrated reperfusion of the hemisphere, through collateral flow. The patient's symptoms resolved. We believe this case demonstrates the effectiveness of hypervolemia and inotropic support in the treatment of acute embolic stroke by inducing dilatation of the leptomeningeal collateral circulation.

Citations

Mar 15, 2008·Stroke; a Journal of Cerebral Circulation·Hwa Kyoung ShinCenk Ayata
Mar 26, 2016·Clinical Case Reports·Hannah FuhrerWolf-Dirk Niesen
Dec 3, 2009·Critical Care Nursing Clinics of North America·Anne W Wojner Alexandrov
Sep 15, 2009·Lancet Neurology·Valérie TikhonoffJan A Staessen
Jun 22, 2007·Journal of the Neurological Sciences·Robert J Wityk
Jul 19, 2017·Frontiers in Neurology·Robert W RegenhardtThabele M Leslie-Mazwi
Feb 5, 2000·Stroke; a Journal of Cerebral Circulation·R SaxenaA H van Den Meiracker
May 6, 2006·Stroke; a Journal of Cerebral Circulation·Amit K MistriJohn F Potter
Feb 18, 2005·Journal of Hypertension·J PotterUNKNOWN CHHIPS Trial Group

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