journal cover

Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor

Nature Medicine

Apr 3, 2002

O V VolpertNoël Bouck

Abstract

Natural inhibitors of angiogenesis are able to block pathological neovascularization without harming the preexisting vasculature. Here we show that two such inhibitors, thrombospondin-1 and pigment epithelium-derived factor, derive specificity for remodeling vessels from their dependenc...read more

Mentioned in this Paper

Procaspase-8
Pigment epithelium-derived factor
Casp9 protein, mouse
Casp8 protein, mouse
Apoptosis, Intrinsic Pathway
Angiogenic Process
FAS gene
FASLG protein, human
FASLG wt Allele
Tumor Angiogenesis
66
1
Paper Details
References
  • References33
  • Citations200
1234
  • References33
  • Citations200
12345...

Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor

Nature Medicine

Apr 3, 2002

O V VolpertNoël Bouck

PMID: 11927940

DOI: 10.1038/nm0402-349

Abstract

Natural inhibitors of angiogenesis are able to block pathological neovascularization without harming the preexisting vasculature. Here we show that two such inhibitors, thrombospondin-1 and pigment epithelium-derived factor, derive specificity for remodeling vessels from their dependenc...read more

Mentioned in this Paper

Procaspase-8
Pigment epithelium-derived factor
Casp9 protein, mouse
Casp8 protein, mouse
Apoptosis, Intrinsic Pathway
Angiogenic Process
FAS gene
FASLG protein, human
FASLG wt Allele
Tumor Angiogenesis
66
1

Related Papers

Paper Details
References
  • References33
  • Citations200
1234
  • References33
  • Citations200
12345...
/papers/inducer-stimulated-fas-targets-activated/11927940