PMID: 15379641Sep 24, 2004Paper

Inducible nitric oxide synthase inhibition by mycophenolic acid

Mini Reviews in Medicinal Chemistry
Dj MiljkovicVladimir Trajkovic

Abstract

The focus of this review is the influence of an immunosuppressive xenobiotic drug mycophenolic acid on the induction of nitric oxide production in various cell types. The potential therapeutic significance of the cell-specific fine-tuning of nitric oxide release by mycophenolic acid, as well as the mechanisms behind the drug action are discussed.

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