Inducible, transferable resistance to vancomycin in Enterococcus faecium, D399

The Journal of Antimicrobial Chemotherapy
D M ShlaesR Williamson

Abstract

Enterococcus faecium D399 was isolated from the blood and peritoneal abscess of a patient with intraabdominal sepsis. The patient had not been treated with vancomycin, but the strain was found to be resistant with a MIC of 1000 mg/l. Resistance was inducible and transferable (probably by conjugation) to JH2-2, and correlated with induction of synthesis of a 39 kDa protein. This mechanism appears to be identical to that previously described for E. faecalis A256, suggesting that dissemination of this form of glycopeptide resistance has already occurred. The resistance phenotype of D399, however, differed somewhat from that found in other enterococcal strains with inducible resistance.

Citations

Feb 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D M Shlaes, B Binczewski
May 1, 1993·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M Guiney, G Urwin
Jan 1, 1991·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·H F GuiotF W Sebens
Sep 1, 1991·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E A BryceA M Clarke
Jun 15, 1990·FEMS Microbiology Letters·S al-ObeidE Collatz
Jul 1, 1996·Diagnostic Microbiology and Infectious Disease·H F BonillaM J Zervos
Dec 1, 1989·Epidemiology and Infection·R C George, A H Uttley
Oct 1, 1995·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·W Witte, I Klare
Sep 1, 1990·Antimicrobial Agents and Chemotherapy·D F Sahm, L Olsen
Jan 1, 1992·Antimicrobial Agents and Chemotherapy·L GutmannJ van Heijenoort
Jul 1, 1992·Antimicrobial Agents and Chemotherapy·S VincentD M Shlaes
Oct 19, 2000·Antimicrobial Agents and Chemotherapy·T M MurphyW J Weiss
Jan 17, 2002·Acta Microbiologica Et Immunologica Hungarica·F RozgonyiA Ghidán
Jan 25, 2003·Journal of Medical Microbiology·Edet E UdoTulsi D Chugh
Jan 1, 1991·Scandinavian Journal of Infectious Diseases·W E PeetermansH F Guiot
May 1, 1993·Annals of Saudi Medicine·S H QadriJ M Burdette
Feb 1, 2019·Clinical Microbiology Reviews·Mónica García-Solache, Louis B Rice
Jun 1, 1996·The Annals of Pharmacotherapy·A S Gin, G G Zhanel
Jul 1, 1990·Clinical Microbiology Reviews·A P JohnsonR C George
Nov 1, 1996·Antimicrobial Agents and Chemotherapy·T M CoqueB E Murray

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