Jan 1, 1981

Induction and characterization of suppressor T cells and soluble factors with modified timothy grass pollen AgB

International Archives of Allergy and Applied Immunology
A MalleyC J Brandt

Abstract

Previous studies demonstrated that antigen B (AgB), a major antigen of timothy grass pollen, modified by photooxidation (Ox-AgB) does not react with rabbit, human, or mouse antibodies directed against AgB and does not induce antibodies reactive with either native or modified AgB. However, immunization of mice with Ox-AgB in alum induces significant T helper cell activity. In this review, we describe the conditions and kinetics for Ox-AgB induction of T suppressor cells, the secretion of AgB-specific T suppressor factor (TSF), and the partial purification of AgB-specific TSF.

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Citations

Mentioned in this Paper

Suppressor T Cells (Lab Test)
T-Lymphocyte
Timothy grass pollen
Spleen
Passive Cutaneous Anaphylaxis
Aluminum potassium sulfate
Adsorption
Process of Secretion
B-Lymphocytes
Soluble

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