PMID: 2495266Apr 1, 1989Paper

Induction and metabolite regulation of levanase synthesis in Bacillus subtilis

Journal of Bacteriology
I MartinG Rapoport

Abstract

Levanase expression in Bacillus subtilis was studied by using transcriptional and translational fusions. It was shown that the degradative products of levan or inulin and low concentrations of fructose were able to induce levanase expression. In the wild-type strain and in a constitutive overproducing sacL mutant, levanase synthesis was repressed by glucose or fructose. This catabolite repression was partially abolished in the derepressed alpha-amylase gra-26 mutant. The levanase gene (sacC) appears to be the distal gene of an operon transcribed from a fructose-inducible promoter. Deletion mapping experiments and primer extension analysis revealed a transcriptional start point located 2.7 kilobases upstream from the sacC gene. Two constitutive sacL mutations were shown to be closely linked by transformation to the sacC gene. The sacL6 and sacL8 mutations were mapped in the promoter-proximal region of the operon.

References

Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Nov 24, 1979·Nucleic Acids Research·H C Birnboim, J Doly
Jan 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·J B Perkins, P J Youngman
Jun 1, 1987·Molecular & General Genetics : MGG·I MartinG Rapoport
Aug 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·S N CohenL Hsu
Jan 1, 1972·Molecular & General Genetics : MGG·J A LepesantR Dedonder
Jun 1, 1968·Archives of Oral Biology·T DaCosta, R J Gibbons
Jul 1, 1968·Archives of Oral Biology·J van Houte, H M Jansen
Jan 1, 1984·Annual Review of Genetics·O Raibaud, M Schwartz
Jun 1, 1983·Journal of Bacteriology·F A FerrariJ A Hoch
Jan 1, 1983·Advances in Applied Microbiology·E J Vandamme, D G Derycke
May 1, 1961·Journal of Bacteriology·C Anagnostopoulos, J Spizizen

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Citations

Aug 5, 1997·Proceedings of the National Academy of Sciences of the United States of America·A GalinierI Martin-Verstraete
Sep 13, 2002·Bioscience, Biotechnology, and Biochemistry·Toshio ShidaJunichi Sekiguchi
Aug 26, 2010·FEMS Microbiology Letters·Massimiliano MarvasiLilliam Casillas Martinez
May 11, 2004·Microbiology·Safia ArousYann Héchard
Jan 18, 2006·Journal of Molecular Microbiology and Biotechnology·Rana HerroJosef Deutscher
Dec 13, 2006·Microbiology and Molecular Biology Reviews : MMBR·Josef DeutscherPieter W Postma
Jul 24, 2007·Applied and Environmental Microbiology·Yong Jun GohRobert W Hutkins
Mar 29, 2001·Journal of Bacteriology·N O AliM Debarbouille
Mar 1, 1995·Microbiological Reviews·W G Haldenwang
May 1, 1995·Applied and Environmental Microbiology·E WankerH Schwab
Sep 1, 1991·Research in Microbiology·M DébarbouilléG Rapoport
Nov 1, 1993·Journal of Bacteriology·F J GrundyT M Henkin
May 1, 1993·Journal of Bacteriology·G L Blatch, D R Woods
Dec 1, 1995·Journal of Bacteriology·I Martin-VerstraeteG Rapoport
Aug 25, 2021·International Journal of Biological Macromolecules·Iolanda CorradoCinzia Pezzella

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