PMID: 6159055Aug 1, 1980Paper

Induction of a cell wall variant of the gonococcus by human amylase

The British Journal of Venereal Diseases
A MellershI Geary

Abstract

Human amylase has been shown to be an effective and powerful inhibitor of the gonococcus in vitro. Its action appears to be on the bacterial cell wall. When tested in osmotically stabilised liquid media the organism was not inhibited; however the organisms which grew in such cultures appeared to be cell wall variants, which were less sensitive to penicillin than the parent strains. Studies on these variants suggest that they are "transitional-phase variants." Since cervical mucus has much in common with an alkaline osmotically stabilised liquid medium and also contains a high concentration of amylase, it seems possible that these variants may occur in vivo.

References

Feb 1, 1979·The British Journal of Venereal Diseases·A MellershS Hafiz
Feb 1, 1976·Japanese Journal of Microbiology·F OtaB B Diena
Dec 1, 1976·The British Journal of Venereal Diseases·S Hafiz, M G McEntegart
Apr 1, 1971·The Journal of Infectious Diseases·Z A McGeeP Charache
Dec 1, 1971·The British Journal of Venereal Diseases·N M Ovcinnikov, V V Delektorskij

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